Apoptosis and Paraptosis Induced by Disulfiram-Loaded Ca2+/Cu2+ Dual-Ions Nano Trap for Breast Cancer Treatment
Z Guo, X Gao, J Lu, Y Li, Z Jin, A Fahad, NU Pambe… - ACS …, 2024 - ACS Publications
Regarded as one of the hallmarks of tumorigenesis and tumor progression, the evasion of
apoptotic cell death would also account for treatment resistance or failure during cancer …
apoptotic cell death would also account for treatment resistance or failure during cancer …
Targeting paraptosis in cancer: opportunities and challenges
F Chen, H Tang, X Cai, J Lin, L Xiang, R Kang… - Cancer Gene …, 2024 - nature.com
Cell death can be classified into two primary categories: accidental cell death and regulated
cell death (RCD). Within RCD, there are distinct apoptotic and non-apoptotic cell death …
cell death (RCD). Within RCD, there are distinct apoptotic and non-apoptotic cell death …
A Nanorobotics-Based Approach of Breast Cancer in the Nanotechnology Era
We are living in an era of advanced nanoscience and nanotechnology. Numerous
nanomaterials, culminating in nanorobots, have demonstrated ingenious applications in …
nanomaterials, culminating in nanorobots, have demonstrated ingenious applications in …
Paraptotic Cell Death as an Unprecedented Mode of Action Observed for New Bipyridine-Silver (I) Compounds Bearing Phosphane Coligands
RG Teixeira, A Stefanelli, A Pilon… - Journal of medicinal …, 2024 - ACS Publications
In this work, we investigated the anticancer activity of several novel silver (I) 2, 2′-bipyridine
complexes containing either triphenylphosphane (PPh3) or 1, 2-bis (diphenylphosphino) …
complexes containing either triphenylphosphane (PPh3) or 1, 2-bis (diphenylphosphino) …
Cannabidiol induces ERK activation and ROS production to promote autophagy and ferroptosis in glioblastoma cells
NY Kim, SGS Gowda, SG Lee, G Sethi… - Chemico-Biological …, 2024 - Elsevier
Small molecule-driven ERK activation is known to induce autophagy and ferroptosis in
cancer cells. Herein the effect of cannabidiol (CBD), a phytochemical derived from Cannabis …
cancer cells. Herein the effect of cannabidiol (CBD), a phytochemical derived from Cannabis …
The Role of Curcumin in Cancer: A Focus on the PI3K/Akt Pathway
Simple Summary Cancer has a major impact on societies across the world. In an attempt to
find new treatment options for cancer, attention has shifted to natural compounds. Curcumin …
find new treatment options for cancer, attention has shifted to natural compounds. Curcumin …
Zearalenone Induces Blood-Testis Barrier Damage through Endoplasmic Reticulum Stress-Mediated Paraptosis of Sertoli Cells in Goats
T Liu, G Liu, Y Xu, Y Huang, Y Zhang, Y Wu… - International Journal of …, 2023 - mdpi.com
Zearalenone (ZEA) is present worldwide as a serious contaminant of food and feed and
causes male reproductive toxicity. The implication of paraptosis, which is a nonclassical …
causes male reproductive toxicity. The implication of paraptosis, which is a nonclassical …
Novel Ultrastructural Insights into the Clear-Cell Carcinoma of the Pancreas: A Case Report
V Giansante, L Di Angelo, C Calabrese… - International Journal of …, 2024 - mdpi.com
Pancreatic cancer, most frequently as ductal adenocarcinoma (PDAC), is the third leading
cause of cancer death. Clear-cell primary adenocarcinoma of the pancreas (CCCP) is a …
cause of cancer death. Clear-cell primary adenocarcinoma of the pancreas (CCCP) is a …
Blood-brain barrier-penetrative fluorescent anticancer agents triggering paraptosis and ferroptosis for glioblastoma therapy
J Wang, M Cao, L Han, P Shangguan, Y Liu, Y Zhong… - 2024 - chemrxiv.org
Currently used drugs for glioblastoma (GBM) treatments are ineffective, primarily due to the
significant challenges posed by strong drug resistance, poor blood-brain barrier (BBB) …
significant challenges posed by strong drug resistance, poor blood-brain barrier (BBB) …