In mammals, secretin is a 27-amino acid peptide that was first studied in 1902 by Bayliss
and Starling from the extracts of the jejunal mucosa for its ability to stimulate pancreatic …

The neuropeptides orexins and their G protein-coupled receptors, OX1 and OX2, were
discovered in 1998, and since then, their role has been investigated in many functions …

At the end of the 20th century, two new neuropeptides (Orexin-A/hypocretin-1 and Orexin-
B/hypocretins-2) expressed in hypothalamus as a prepro-orexins precursor, were …

The orexins, also referred to as hypocretins, are neuropeptides that originate from the lateral
hypothalamus (LH) region of the brain. They are composed of two small peptides, orexin-A …

Orexin is a neuropeptide distributed widely among vertebrates. In mammals, orexin and its
receptor system are involved in the regulation of food intake, locomotion, and psychomotor …

The teleost fish-specific genome duplication gave rise to a great number of species
inhabiting diverse environments with different access to nutrients and life histories. This …

Orexin acts as an orexigenic factor for the regulation of appetite and rhythmicity in rodents. In
goldfish, intracerebroventricular (ICV) administration of orexin A has been shown to affect …

Although a precise definition of “sleep” has yet to be established, sleep-like behaviors have
been observed in all animals studied to date including mammals and nonmammalian …

Exendins are secretin hormone-like peptides that are components of the toxins from two
venomous lizards, Heloderma suspectum (Gila monster) and Heloderma horridium …

The genes encoding the peptide precursors for glucagon (GCG), glucose-dependent
insulinotropic peptide (GIP), and ortholog of exendin belong to the same family as shown by …