Great progress has been made in recent years to reduce the high level of suffering caused
by malaria worldwide. Notably, the use of insecticide-treated mosquito nets for malaria …

Specialized plant terpenoids have found fortuitous uses in medicine due to their
evolutionary and biochemical selection for biological activity in animals. However, these …

The antimalarial drug artemisinin and its derivatives have been explored as potential
anticancer agents, but their underlying mechanisms are controversial. In this study, we found …

Given the increase in antibiotic-resistant bacteria, alongside the alarmingly low rate of newly
approved antibiotics for clinical usage, we are on the verge of not having effective treatments …

Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …

Malaria is a highly inflammatory and oxidative disease. The production of reactive oxygen
species by host phagocytes is an essential component of the host response to Plasmodium …

Recent developments in synthetic biology, combined with continued progress in systems
biology and metabolic engineering, have enabled the engineering of microorganisms to …

Background There has been a significant increase in the cost and timeline of delivering new
drugs for clinical use over the last three decades. Despite the increased investments in …

This article gives a very brief overview of the antibiotic era, beginning from the discovery of
first antibiotics until the present day situation, which is marred by the emergence of hard-to …

Antimalarial drugs are key tools for the control and elimination of malaria. Recent decreases
in the global malaria burden are likely due, in part, to the deployment of artemisinin-based …