Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome; its rising prevalence parallels the rise in obesity and diabetes. Historically …

Metabolic syndrome (MS) represents worldwide public health issue characterized by a set of
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …

Insulin resistance is the primary pathophysiology underlying metabolic syndrome and type 2
diabetes,. Previous metagenomic studies have described the characteristics of gut …

Evidence suggests that excessive intake of added sugars has adverse effects on
cardiometabolic health, which is consistent with many reviews and consensus reports from …

Hepatic de novo lipogenesis (DNL) is the biochemical process of synthesising fatty acids
from acetyl‐CoA subunits that are produced from a number of different pathways within the …

Obesity is a chronic disease that represents one of the most serious global health burdens
associated to an excess of body fat resulting from an imbalance between energy intake and …

Nonalcoholic Fatty Liver Disease (NAFLD) represents the leading cause of liver disease in
developed countries but its diffusion is currently also emerging in Asian countries, in South …

Adipose tissue and the liver play significant roles in the regulation of whole-body energy
homeostasis, but they have not evolved to cope with the continuous, chronic, nutrient …

Among various factors, such as an unhealthy diet or a sedentarity lifestyle, excessive
fructose consumption is known to favor nonalcoholic fatty liver disease (NAFLD), as fructose …

Background As a result of the increased consumption of sugar-rich and fatty-products, and
the increase in preference for such products, metabolic disorders are becoming more …