Neurodegenerative diseases are characterized by the progressive loss of neurons in
different regions of the nervous system. Alzheimer's disease (AD) and Parkinson's disease …

Background With no current cure for mild cognitive impairment (MCI), delaying its
progression could significantly reduce the disease burden and improve the quality of life for …

Alzheimer's disease is a neurodegenerative disorder in which the pathological accumulation
of amyloid-β and tau begins years before symptom onset. Emerging evidence suggests that …

Background Studies have shown that the prevalence of dementia in Latin America and the
Caribbean (LAC) may be higher than in high-income countries. Thus, we sought to …

Gut microbiota represents a diverse and dynamic population of microorganisms harbouring
the gastrointestinal tract, which influences host health and disease. Bacterial colonization of …

Background Sex differences in major cardiovascular risk factors for incident (fatal or non-
fatal) all-cause dementia were assessed in the UK Biobank. The effects of these risk factors …

Many neurodegenerative diseases are rooted in the activities of amyloid-like proteins which
possess conformations that spread to healthy proteins. These include Alzheimer's disease …

Dementia is one of the greatest global challenges for public health; however, the
relationship between anticholinergic drugs and dementia remains unclear. The aim of the …

Extra-virgin olive oil (EVOO), a popular functional food and major source of fat in the
Mediterranean diet, possesses a variety of healthful components, including …

Background With population aging, the economic burden of dementia is growing in Europe.
Understanding the economic costs of dementia provides an important basis for prioritization …