Background The effect of corticosteroids on clinical outcomes in patients with influenza
pneumonia remains controversial. We aimed to further evaluate the influence of …

Background: Community-acquired pneumonia (CAP) is common and often severe. Purpose:
To examine the effect of adjunctive corticosteroid therapy on mortality, morbidity, and …

Abstract Background In late December 2019, an outbreak of acute respiratory illness,
coronavirus disease 2019 (COVID-19), emerged in Wuhan, China. We aimed to study the …

The Faculty of Intensive Care Medicine and Intensive Care Society Guideline Development
Group have used GRADE methodology to make the following recommendations for the …

The acute respiratory distress syndrome (ARDS) is a form of severe hypoxemic respiratory
failure that is characterized by inflammatory injury to the alveolar capillary barrier, with …

Acute respiratory distress syndrome (ARDS) is the often fatal sequelae of a broad range of
precipitating conditions. Despite decades of intensive research and clinical trials there …

Glucocorticoid resistance or insensitivity is a major barrier to the treatment of several
common inflammatory diseases—including chronic obstructive pulmonary disease and …

Innate immunity normally provides excellent defence against invading microorganisms.
Acute inflammation is a form of innate immune defence and represents one of the primary …

Acute lung injury (ALI) represents a serious heterogenous pulmonary disorder with high
mortality. Despite improved understanding of the pathophysiology, the efficacy of standard …

Acute respiratory distress syndrome (ARDS) occurs when a diverse array of triggers cause
acute, bilateral pulmonary inflammation and increased pulmonary capillary permeability …