Nowadays, one of the major global health concerns is coronavirus disease 2019 (COVID-
19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …

Cytokine storm is a phenomenon characterized by strong elevated circulating cytokines that
most often occur after an overreactive immune system is activated by an acute systemic …

Chronic unresolving inflammation is emerging as a key underlying pathological feature of
many if not most diseases ranging from autoimmune conditions to cardiometabolic and …

Rationale: Resolution mechanisms are central in both the maintenance of homeostasis and
the return to catabasis following tissue injury and infections. Among the proresolving …

Coagulation disorders, endotheliopathy and inflammation are the most common hallmarks
in SARS-CoV-2 infection, largely determining COVID-19's outcome and severity …

The unprecedented impact of the coronavirus disease 2019 (COVID-19) pandemic has
resulted in global challenges to our health-care systems and our economic security. As …

Cytokine storms are a primary cause of multiple organ damage and death after severe
infections, such as SARS-CoV-2. However, current single cytokine-targeted strategies …

Heart disease is a significant burden on global health care systems and is a leading cause
of death each year. To improve our understanding of heart disease, high quality disease …

The benefits of baricitinib in coronavirus disease‐2019 are inadequately defined. We
performed a systematic review and meta‐analysis of studies of baricitinib to determine its …