Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global public health
emergency and has led to devastating results. Mounting evidence proposes that the disease …

Mechanics insights of alpha-lipoic acid against cardiovascular diseases during COVID-19 infection

L Rochette, S Ghibu - International Journal of Molecular Sciences, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China, in late December
2019. Since then, COVID-19 has spread rapidly worldwide and was declared a global …

[PDF][PDF] The role of vitamin C in human immunity and its treatment potential against COVID-19: a review article

A Moore, D Khanna - Cureus, 2023 - cureus.com
The outbreak of the COVID-19 pandemic has left clinicians around the world searching for
viable prevention and treatment options to use against the virus. The important physiologic …

COVID-19 hospitalizations, intensive care unit stays, ventilation, and death among patients with immune-mediated inflammatory diseases compared to controls

L Eder, R Croxford, AM Drucker, A Mendel… - The Journal of …, 2022 - jrheum.org
Objective To investigate coronavirus disease 2019 (COVID-19) hospitalization risk in
patients with immune-mediated inflammatory diseases (IMIDs) compared with matched non …

[HTML][HTML] Obesity and severe coronavirus disease 2019: molecular mechanisms, paths forward, and therapeutic opportunities

T Yan, R Xiao, N Wang, R Shang, G Lin - Theranostics, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to have higher
pathogenicity among patients with obesity. Obesity, termed as body mass index greater than …

COVID-19 complications: Oxidative stress, inflammation, and mitochondrial and endothelial dysfunction

E Georgieva, J Ananiev, Y Yovchev… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …

The emerging role of neutrophils in the pathogenesis of thrombosis in COVID-19

V Iliadi, I Konstantinidou, K Aftzoglou, S Iliadis… - International journal of …, 2021 - mdpi.com
Previous studies have shown that COVID-19 leads to thrombotic complications, which have
been associated with high morbidity and mortality rates. Neutrophils are the largest …

Inflammatory pathways in COVID‐19: Mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

[HTML][HTML] Distinct characteristics of COVID-19 infection in children

X Han, X Li, Y Xiao, R Yang, Y Wang, X Wei - Frontiers in Pediatrics, 2021 - frontiersin.org
SARS-CoV-2, a member of the family coronaviridae, has triggered a lethal pandemic termed
coronavirus disease 2019 (COVID-19). Pediatric patients, mainly from families with a cluster …