[HTML][HTML] Inspiration for COVID-19 treatment: Network analysis and experimental validation of baicalin for cytokine storm

J You, H Li, P Fan, X Yang, Y Wei, L Zheng… - Frontiers in …, 2022 - frontiersin.org
Background: Cytokine storm (CS) is a systemic inflammatory syndrome and a major cause of
multi-organ failure and even death in COVID-19 patients. With the increasing number of …

Impact of P-selectin–PSGL-1 Axis on Platelet-Endothelium-Leukocyte Interactions in Fatal COVID-19

M Granai, V Warm, A Vogelsberg, J Milla, K Greif… - Laboratory …, 2023 - Elsevier
In critically ill patients infected with SARS-CoV-2, early leukocyte recruitment to the
respiratory system was found to be orchestrated by leukocyte trafficking molecules …

Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality

V Chávez-Valencia, C Orizaga-de-la-Cruz… - Diseases, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a disease caused by infection with the SARS-CoV-
2 virus and has represented one of the greatest challenges humanity has faced in recent …

A brief overview of SARS-CoV-2 infection and its management strategies: a recent update

A Das, S Pathak, M Premkumar… - Molecular and Cellular …, 2023 - Springer
The COVID-19 pandemic has become a global health crisis, inflicting substantial morbidity
and mortality worldwide. A diverse range of symptoms, including fever, cough, dyspnea, and …

[HTML][HTML] Zonulin, a marker of gut permeability, is associated with mortality in a cohort of hospitalised peruvian COVID-19 patients

LA Palomino-Kobayashi, B Ymaña, J Ruiz… - Frontiers in cellular …, 2022 - frontiersin.org
Zonulin has previously been related to intestinal permeability in various inflammatory
diseases, and more recently to the physiopathology of severe COVID-19 infections. We …

Diagnostic significance of serum galectin-3 in hospitalized patients with COVID-19—A preliminary study

B Kuśnierz-Cabala, B Maziarz, P Dumnicka… - Biomolecules, 2021 - mdpi.com
Severe coronavirus disease 2019 (COVID-19) is associated with hyperinflammation leading
to organ injury, including respiratory failure. Galectin-3 was implicated in innate …

Contemporary narrative review of treatment options for COVID‐19

L Shang, DC Lye, B Cao - Respirology, 2021 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) pandemic is ongoing and many drugs
have been studied in clinical trials. From a pathophysiological perspective, anti‐viral drugs …

Targeting the complement–sphingolipid system in COVID-19 and gaucher diseases: evidence for a new treatment strategy

VS Trivedi, AF Magnusen, R Rani, L Marsili… - International Journal of …, 2022 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-induced disease
(COVID-19) and Gaucher disease (GD) exhibit upregulation of complement 5a (C5a) and its …

[HTML][HTML] Predictive value of frailty in the mortality of hospitalized patients with COVID-19: a systematic review and meta-analysis

Y Zou, M Han, J Wang, J Zhao, H Gan… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background The present study aimed to analyze the impact of frailty on mortality risk among
hospitalized patients with coronavirus disease 2019 (COVID-19). Methods Literature …

Lessons from SARS‐CoV, MERS‐CoV, and SARS‐CoV‐2 Infections: What We Know So Far

RT Alsafi - Canadian Journal of Infectious Diseases and …, 2022 - Wiley Online Library
Within past decades, human infections with emerging and reemerging zoonotic viral
pathogens have raised the eminent public health concern. Since November 2002, three …