Current medical approaches to control the Covid-19 pandemic are either to directly target
the SARS-CoV-2 via innovate a defined drug and a safe vaccine or indirectly target the …

The coronavirus disease 2019 (COVID-19) pandemic has claimed over 2.7 million lives
globally. Obesity has been associated with increased severity and mortality of COVID-19 …

Recent evidence proposed that the severity of Coronavirus disease 2019 (COVID-19)
patients is a consequence of cytokine storm, characterized by increased IL-1β, IL-6, IL-18 …

COVID-19 has been a global health problem since 2020. There are different spectrums of
manifestation of this disease, ranging from asymptomatic to extremely severe forms …

Background: Immunomodulatory drugs have been used in patients with severe COVID-19.
The objective of this study was to evaluate the effects of two different strategies, based either …

Hemophagocytic lymphohistiocytosis (HLH) constitutes a life-threatening inflammatory
syndrome. Postmortem histological findings of bone marrow (BM) from COVID-19 patients …

Due to its leading role in fighting infections, the human immune system has been the focus
of many studies in the context of Coronavirus disease 2019 (COVID-19). In a worldwide …

Muscle and adipose tissue produce irisin during exercise. Irisin is thermogenic
adipomyokine, improves glucose and lipid metabolism, and ameliorates the effects of …

Some evidence has indicated that monkeypox can induce a cytokine storm. Purinergic
signaling is a cell pathway related to the cytokine storm. However, the precise mechanisms …

The dysregulated immune response and inflammation resulting in severe COVID-19 are still
incompletely understood. Having recently determined that aberrant death-ligand-induced …