Maternal immune activation and neuroinflammation in human neurodevelopmental disorders

VX Han, S Patel, HF Jones, RC Dale - Nature Reviews Neurology, 2021 - nature.com
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …

Maternal acute and chronic inflammation in pregnancy is associated with common neurodevelopmental disorders: a systematic review

VX Han, S Patel, HF Jones, TC Nielsen… - Translational …, 2021 - nature.com
Inflammation is increasingly recognized as a cause or consequence of common problems of
humanity including obesity, stress, depression, pollution and disease states such as …

Immunological causes of obsessive-compulsive disorder: is it time for the concept of an “autoimmune OCD” subtype?

D Endres, TA Pollak, K Bechter, D Denzel… - Translational …, 2022 - nature.com
Obsessive-compulsive disorder (OCD) is a highly disabling mental illness that can be
divided into frequent primary and rarer organic secondary forms. Its association with …

[HTML][HTML] Clinical advances in obsessive-compulsive disorder: a position statement by the International College of Obsessive-Compulsive Spectrum Disorders

NA Fineberg, E Hollander, S Pallanti… - International clinical …, 2020 - journals.lww.com
In this position statement, developed by The International College of Obsessive-Compulsive
Spectrum Disorders, a group of international experts responds to recent developments in the …

Neutrophil-lymphocyte ratios as inflammatory biomarkers in psychiatric patients

T Bhikram, P Sandor - Brain, behavior, and immunity, 2022 - Elsevier
Purpose There is a growing amount of evidence to suggest that inflammation may have a
role in the onset and prognosis of psychiatric disorders. We reviewed the literature of studies …

[HTML][HTML] Treatment-resistant OCD: Pharmacotherapies in adults

PJ Van Roessel, G Grassi, EN Aboujaoude… - Comprehensive …, 2023 - Elsevier
Serotonin reuptake inhibitor (SRI) medications are well established as first-line
pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD). However …

Obsessive-compulsive disorder: autoimmunity and neuroinflammation

M Gerentes, A Pelissolo, K Rajagopal… - Current psychiatry …, 2019 - Springer
Abstract Purpose of Review Here, we propose to review the immuno-inflammatory
hypothesis in OCD given the concurrent incidence of autoimmune comorbidities, infectious …

Neuroscientifically informed formulation and treatment planning for patients with obsessive-compulsive disorder: a review

DD Dougherty, BP Brennan, SE Stewart… - Jama …, 2018 - jamanetwork.com
Importance Obsessive-compulsive disorder (OCD) is a common and often debilitating
psychiatric illness. Recent advances in the understanding of the neuroscience of OCD have …

Developmental considerations in obsessive compulsive disorder: comparing pediatric and adult-onset cases

DA Geller, S Homayoun, G Johnson - Frontiers in Psychiatry, 2021 - frontiersin.org
There appear to be two peaks of incidence of Obsessive Compulsive Disorder (OCD), one
with a pre-adolescent onset and another in early adulthood. As new cases are added, the …

Association of maternal autoimmune disease with attention-deficit/hyperactivity disorder in children

TC Nielsen, N Nassar, AW Shand, H Jones… - JAMA …, 2021 - jamanetwork.com
Importance Maternal autoimmune disease has been associated with increased risk of
neurodevelopmental disorders in offspring, but few studies have assessed the association …