E De Clercq - Biochemical pharmacology, 2013 - Elsevier
Vaccination is possible to prevent infections with some viruses: hepatitis B virus (HBV), varicella-zoster virus (VZV), influenza A and B viruses, Yellow fever virus and poliovirus; but …
Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2. 2.22) that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …
E De Clercq - Annual review of pharmacology and toxicology, 2011 - annualreviews.org
My search for a selective antiviral chemotherapy started more than 40 years ago with interferon inducers, then shifted to nucleoside analogs with the discovery of BVDU …
IA Mikhailopulo, AI Miroshnikov - Mendeleev Communications, 2011 - academia.edu
Mendeleev Communications Page 1 i VOLUME 21 NUMBER 2 2011 MENCEX (2) 57 – 114 (2011) Mendeleev Communications CONTENTS O X O P OH O O O B Y Z O X B1 Y Z – B1 O …
E De Clercq - Journal of medicinal chemistry, 2010 - ACS Publications
In 1959 Bill Prusoff described the synthesis of idoxuridine (5-iodo-2 0-deoxyuridine, IDUa), 1 later to become the first antiviral drug to be licensed for clinical use. This marked the birthday …
IA Mikhailopulo, AI Miroshnikov - Acta Naturae (англоязычная …, 2010 - cyberleninka.ru
This review focuses on new trends in nucleoside biotechnology, which have emerged during the last decade. Continuously growing interest in the study of this class of compounds …
P Colson, D Raoult - International journal of antimicrobial agents, 2016 - ncbi.nlm.nih.gov
Viruses are a serious threat for humans worldwide because there are in their ranks many causative agents of potentially fatal infections and cancers [1, 2]. Despite this, emerging or re …
The anti-HIV-1 activity of mangiferin was evaluated. Mangiferin can inhibit HIV-1ⅢB induced syncytium formation at non-cytotoxic concentrations, with a 50% effective concentration …
MI Kharitonova, ID Konstantinova… - Russian Chemical …, 2018 - iopscience.iop.org
The review systematically covers experimental data on the synthesis of modified benzimidazole nucleosides and evaluation of their biological activity published mainly over …