[HTML][HTML] Exploring protein-protein interactions at the proteome level

H Elhabashy, F Merino, V Alva, O Kohlbacher… - Structure, 2022 - cell.com
Proteins are central to all of the processes of life. For their activity, they almost invariably
need to interact with other macromolecules, be they nucleic acids, membranes, glycans, or …

Computational cardiac physiology for new modelers: Origins, foundations, and future

JT Koivumäki, J Hoffman, MM Maleckar… - Acta …, 2022 - Wiley Online Library
Mathematical models of the cardiovascular system have come a long way since they were
first introduced in the early 19th century. Driven by a rapid development of experimental …

Identifying patterns of immune related cells and genes in the peripheral blood of acute myocardial infarction patients using a small cohort

PF Zheng, QC Zou, LZ Chen, P Liu, ZY Liu… - Journal of Translational …, 2022 - Springer
Background The immune system plays a vital role in the pathophysiology of acute
myocardial infarction (AMI). However, the exact immune related mechanism is still unclear …

[HTML][HTML] A novel lncRNA-miRNA-mRNA triple network identifies lncRNA XIST as a biomarker for acute myocardial infarction

PF Zheng, LZ Chen, P Liu, HW Pan - Aging (albany NY), 2022 - ncbi.nlm.nih.gov
A novel lncRNA-miRNA-mRNA triple network identifies lncRNA XIST as a biomarker for acute
myocardial infarction - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Integrated analysis of inflammatory mRNAs, miRNAs, and lncRNAs elucidates the molecular interactome behind bovine mastitis

A Hasankhani, M Bakherad, A Bahrami… - Scientific Reports, 2023 - nature.com
Mastitis is known as intramammary inflammation, which has a multifactorial complex
phenotype. However, the underlying molecular pathogenesis of mastitis remains poorly …

Connections for matters of the heart: network medicine in cardiovascular diseases

AR Sonawane, E Aikawa, M Aikawa - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Cardiovascular diseases (CVD) are diverse disorders affecting the heart and vasculature in
millions of people worldwide. Like other fields, CVD research has benefitted from the deluge …

Identification of hub genes in digestive system of mandarin fish (Siniperca chuatsi) fed with artificial diet by weighted gene co-expression network analysis

Y Shen, L Song, T Chen, H Jiang, G Yang… - … and Physiology Part D …, 2023 - Elsevier
Mandarin fish (Siniperca chuatsi) is a carnivorous freshwater fish and an economically
important species. The digestive system (liver, stomach, intestine, pyloric caecum …

Exploring breast cancer exosomes for novel biomarkers of potential diagnostic and prognostic importance

DB Alagundagi, SD Ghate, VKJ Rajendra, P Gollapalli… - 3 Biotech, 2023 - Springer
The comprehensive bioinformatics analysis of breast cancer exosomes revealed that
HSP90AA1, CCT2, and ENO1 were novel hub genes in the giant protein–protein interaction …

Identification of potential pseudogenes for predicting the prognosis of hepatocellular carcinoma

L Ge, T Jin, W Zhang, Z Zhang, Y Zhang, X Hu… - Journal of Cancer …, 2023 - Springer
Purpose Hepatocellular carcinoma (HCC) remains a highly deadly malignant tumor with
high recurrence and metastasis rates. Cancer stem cells (CSCs) are involved in tumor …

Identification of modules and key genes associated with breast cancer subtypes through network analysis

MD Mares-Quiñones, E Galán-Vásquez… - Scientific Reports, 2024 - nature.com
Breast cancer is the most common malignancy in women around the world. Intratumor and
intertumoral heterogeneity persist in mammary tumors. Therefore, the identification of …