[HTML][HTML] Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics

P Mi - Theranostics, 2020 - ncbi.nlm.nih.gov
In recent years, much progress has been motivated in stimuli-responsive nanocarriers,
which could response to the intrinsic physicochemical and pathological factors in diseased …

Stimuli-responsive nano-architecture drug-delivery systems to solid tumor micromilieu: past, present, and future perspectives

HS El-Sawy, AM Al-Abd, TA Ahmed, KM El-Say… - ACS …, 2018 - ACS Publications
The microenvironment characteristics of solid tumors, renowned as barriers that harshly
impeded many drug-delivery approaches, were precisely studied, investigated, categorized …

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

M Karimi, A Ghasemi, PS Zangabad… - Chemical Society …, 2016 - pubs.rsc.org
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …

Engineered nanoparticles for drug delivery in cancer therapy

T Sun, YS Zhang, B Pang, DC Hyun… - Nanomaterials and …, 2021 - taylorfrancis.com
In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …

Stimuli-responsive nanocarriers for drug delivery

S Mura, J Nicolas, P Couvreur - Nature materials, 2013 - nature.com
Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive
devices that deliver a drug in spatial-, temporal-and dosage-controlled fashions have …

Mechanisms of drug release in nanotherapeutic delivery systems

PT Wong, SK Choi - Chemical reviews, 2015 - ACS Publications
Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …

Hierarchical targeting strategy for enhanced tumor tissue accumulation/retention and cellular internalization

S Wang, P Huang, X Chen - Advanced Materials, 2016 - Wiley Online Library
Targeted delivery of therapeutic agents is an important way to improve the therapeutic index
and reduce side effects. To design nanoparticles for targeted delivery, both enhanced tumor …

Recent advances in nanoparticle-based cancer drug and gene delivery

N Amreddy, A Babu, R Muralidharan… - Advances in cancer …, 2018 - Elsevier
Effective and safe delivery of anticancer agents is among the major challenges in cancer
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …

In Vivo Biomolecule Corona around Blood-Circulating, Clinically Used and Antibody-Targeted Lipid Bilayer Nanoscale Vesicles

M Hadjidemetriou, Z Al-Ahmady, M Mazza, RF Collins… - ACS …, 2015 - ACS Publications
The adsorption of proteins and their layering onto nanoparticle surfaces has been called the
“protein corona”. This dynamic process of protein adsorption has been extensively studied …

[HTML][HTML] Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all

AL Oei, LEM Vriend, J Crezee, NAP Franken… - Radiation …, 2015 - Springer
The currently available arsenal of anticancer modalities includes many DNA damaging
agents that can kill malignant cells. However, efficient DNA repair mechanisms protect both …