Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide,
with high rates of recurrence and death. Surgical resection and ablation therapy have limited …

In the last decade, it has been well-established that tumor-infiltrating myeloid cells fuel not
only the process of carcinogenesis through cancer-related inflammation mechanisms, but …

The Immunoscore is a method to quantify the immune cell infiltration within cancers to
predict the disease prognosis. Previous immune profiling approaches relied on limited …

The lung tumor microenvironment, which is composed of heterogeneous cell populations,
plays an important role in the progression of lung cancer and is closely related to therapeutic …

Tumour-associated macrophages (TAMs) are essential players in the tumour
microenvironment (TME) and modulate various pro-tumorigenic functions such as …

The unique environment of the lungs is protected by complex immune interactions. Human
lung tissue-resident memory T cells (TRM) have been shown to position at the pathogen …

Macrophages are one of the most important cells of the innate immune system and are
known for their ability to engulf and digest foreign substances, including cellular debris and …

Background Lipid metabolism has been implicated in a variety of normal cellular processes
and strongly related to the development of multiple diseases, including tumor. Tumor …

Macrophages are potent immune effector cells in innate immunity and exert dual-effects in
the tumor microenvironment (TME). Tumor-associated macrophages (TAMs) make up a …

Background Cancer immunity is based on the interaction of a multitude of cells in the spatial
context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated …