We use UK Biobank data to train predictors for 65 blood and urine markers such as HDL,
LDL, lipoprotein A, glycated haemoglobin, etc. from SNP genotype. For example, our …

We develop a new method, SBayesRC, that integrates GWAS summary statistics with
functional genomic annotations to improve polygenic prediction of complex traits. Our …

Chronic heavy alcohol use impacts all major neurotransmitter systems and is associated
with multiple medical, psychiatric, and social problems. Available evidence‐based …

Using results from genome-wide association studies for understanding complex traits is a
current challenge. Here we review how genotype data can be used with different machine …

Abstract Background and Aims Genome‐wide association studies (GWAS) of opioid use
disorder (OUD) and cannabis use disorder (CUD) have lagged behind those of alcohol use …

Eating disorders such as anorexia nervosa, bulimia nervosa and binge-eating disorder,
have a deep social impact, concluding with death in cases of severe disease. Eating …

Polygenic scores (PGS) are now commonly available in longitudinal cohort studies, leading
to their integration into epidemiological research. In this work, our aim is to explore how …

Genetic factors contribute significantly to interindividual differences in the susceptibility to
stress‐related disorders. As stress can also be conceptualized as environmental exposure …

Background Genetic risk scores (GRS) summarize genetic features such as single
nucleotide polymorphisms (SNPs) in a single statistic with respect to a given trait. So far …

Many patients with mild traumatic brain injury (mTBI) are at risk for mental health problems
such as posttraumatic stress disorder (PTSD). The objective of this study was to determine …