The relationship between genotype-and phenotype-based estimates of genetic liability to human psychiatric disorders, in practice and in theory
Genetics as a science has roots in studying phenotypes of relatives, but molecular
approaches facilitate direct measurements of genomic variation within individuals …
approaches facilitate direct measurements of genomic variation within individuals …
Loneliness is linked to specific subregional alterations in hippocampus-default network covariation
Social interaction complexity makes humans unique. But in times of social deprivation, this
strength risks exposure of important vulnerabilities. Human social neuroscience studies …
strength risks exposure of important vulnerabilities. Human social neuroscience studies …
Polygenic Risk Scores for Glaucoma Onset in the Ocular Hypertension Treatment Study
Importance Primary open-angle glaucoma (POAG) is a highly heritable disease, with 127
identified risk loci to date. Polygenic risk score (PRS) may provide a clinically useful …
identified risk loci to date. Polygenic risk score (PRS) may provide a clinically useful …
The potential of current polygenic risk scores to predict high myopia and myopic macular degeneration in multiethnic Singapore adults
Purpose To evaluate the transancestry portability of current myopia polygenic risk scores
(PRSs) to predict high myopia (HM) and myopic macular degeneration (MMD) in an Asian …
(PRSs) to predict high myopia (HM) and myopic macular degeneration (MMD) in an Asian …
Dynamic effective connectivity among large‐scale brain networks mediates risk of anxiety
T Tian, D Liu, G Zhang, J Wang, C Wan… - Human Brain …, 2023 - Wiley Online Library
Anxiety is characterized by altered brain networks. Directional information flows among
dynamic brain networks concerning neuropathogenesis of anxiety have not yet been …
dynamic brain networks concerning neuropathogenesis of anxiety have not yet been …
A comprehensive investigation into the genetic relationship between music engagement and mental health
While music engagement is often regarded as beneficial for mental health, some studies
report higher risk for depression and anxiety among musicians. This study investigates …
report higher risk for depression and anxiety among musicians. This study investigates …
Identification of women at high risk of postpartum psychiatric episodes: A population‐based study quantifying relative and absolute risks following exposure to …
Background We quantified relative and absolute risks of postpartum psychiatric episodes
(PPE) following risk factors: Young age, past personal or family history of psychiatric …
(PPE) following risk factors: Young age, past personal or family history of psychiatric …
[PDF][PDF] Gattaca as a lens on contemporary genetics: marking 25 years into the film's “not-too-distant” future
CB Ogbunugafor, MD Edge - Genetics, 2022 - academic.oup.com
The 1997 film Gattaca has emerged as a canonical pop culture reference used to discuss
modern controversies in genetics and bioethics. It appeared in theaters a few years prior to …
modern controversies in genetics and bioethics. It appeared in theaters a few years prior to …
[HTML][HTML] Attitudes towards polygenic risk testing in individuals with glaucoma
GL Hollitt, OM Siggs, B Ridge, MC Keane… - Ophthalmology …, 2022 - Elsevier
Purpose Glaucoma is the leading cause of irreversible blindness worldwide; however, vision
loss resulting from glaucoma generally can be prevented through early identification and …
loss resulting from glaucoma generally can be prevented through early identification and …
Genetic risk, parental history, and suicide attempts in a diverse sample of US adolescents
Background Adolescent suicide is a major health problem in the US marked by a recent
increase in risk of suicidal behavior among Black/African American youth. While genetic …
increase in risk of suicidal behavior among Black/African American youth. While genetic …