Impact of the Delta variant on vaccine efficacy and response strategies

L Bian, Q Gao, F Gao, Q Wang, Q He, X Wu… - Expert review of …, 2021 - Taylor & Francis
ABSTRACT Introduction The Delta variant of SARS-CoV-2 has caused a new wave of the
COVID-19 epidemic in many countries. It is the most infectious variant of SARS-CoV-2 to …

Neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants induced by natural infection or vaccination: a systematic …

X Chen, Z Chen, AS Azman, R Sun, W Lu… - Clinical Infectious …, 2022 - academic.oup.com
Recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
may pose a threat to immunity. A systematic landscape of neutralizing antibodies against …

[HTML][HTML] Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection

Z Wang, F Muecksch, D Schaefer-Babajew, S Finkin… - Nature, 2021 - nature.com
More than one year after its inception, the coronavirus disease 2019 (COVID-19) pandemic
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains difficult …

[HTML][HTML] Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination

A Cho, F Muecksch, D Schaefer-Babajew, Z Wang… - Nature, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection produces B cell
responses that continue to evolve for at least a year. During that time, memory B cells …

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection

AJ Greaney, AN Loes, LE Gentles… - Science translational …, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
with mutations in key antibody epitopes has raised concerns that antigenic evolution could …

Preliminary report on severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Spike mutation T478K

S Di Giacomo, D Mercatelli… - Journal of medical …, 2021 - Wiley Online Library
Several severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants have
emerged, posing a renewed threat to coronavirus disease 2019 containment and to vaccine …

[HTML][HTML] Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

CA Jette, AA Cohen, PNP Gnanapragasam… - Cell reports, 2021 - cell.com
Many anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) neutralizing
antibodies target the angiotensin-converting enzyme 2 (ACE2) binding site on viral spike …

[HTML][HTML] Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants

J Xu, K Xu, S Jung, A Conte, J Lieberman, F Muecksch… - Nature, 2021 - nature.com
Since the start of the COVID-19 pandemic, SARS-CoV-2 has caused millions of deaths
worldwide. Although a number of vaccines have been deployed, the continual evolution of …

[HTML][HTML] B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV

JF Scheid, CO Barnes, B Eraslan, A Hudak, JR Keeffe… - Cell, 2021 - cell.com
Monoclonal antibodies (mAbs) are a focus in vaccine and therapeutic design to counteract
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants. Here, we …

[HTML][HTML] Detection and characterization of the SARS-CoV-2 lineage B. 1.526 in New York

AP West Jr, JO Wertheim, JC Wang… - Nature …, 2021 - nature.com
Abstract Wide-scale SARS-CoV-2 genome sequencing is critical to tracking viral evolution
during the ongoing pandemic. We develop the software tool, Variant Database (VDB), for …