Predictive phage therapy for Escherichia coli urinary tract infections: Cocktail selection for therapy based on machine learning models

M Keith, A Park de la Torriente… - Proceedings of the …, 2024 - National Acad Sciences
This study supports the development of predictive bacteriophage (phage) therapy: the
concept of phage cocktail selection to treat a bacterial infection based on machine learning …

A Game of Resistance: War Between Bacteria and Phages and How Phage Cocktails can be the Solution.

P Costa, C Pereira, JL Romalde, A Almeida - Virology, 2024 - Elsevier
While phages hold promise as an antibiotic alternative, they encounter significant
challenges in combating bacterial infections, primarily due to the emergence of phage …

Bacterial enrichment prior to third-generation metagenomic sequencing improves detection of BRD pathogens and genetic determinants of antimicrobial resistance in …

EK Herman, SR Lacoste, CN Freeman… - Frontiers in …, 2024 - frontiersin.org
Introduction Bovine respiratory disease (BRD) is one of the most important animal health
problems in the beef industry. While bacterial culture and antimicrobial susceptibility testing …

Impact of database choice and confidence score on the performance of taxonomic classification using Kraken2

Y Liu, MH Ghaffari, T Ma, Y Tu - aBIOTECH, 2024 - Springer
Accurate taxonomic classification is essential to understanding microbial diversity and
function through metagenomic sequencing. However, this task is complicated by the vast …

First animal source metagenome assembly of Lawsonella clevelandensis from canine external otitis

AG Tóth, N Solymosi, M Tenk, Z Káldy, T Németh - bioRxiv, 2023 - biorxiv.org
External otitis is one of the most common conditions in dogs to be presented to the
veterinarian. Moreover, the disorder is often difficult to manage. The range and role of …

Clinical considerations on antimicrobial resistance potential of complex microbiological samples

N Solymosi, AG Tóth, SÁ Nagy, I Csabai, C Feczkó… - bioRxiv, 2024 - biorxiv.org
Antimicrobial resistance (AMR) is one of our greatest public health challenges. Targeted use
of antibiotics (AB) can reduce the occurrence and spread of AMR and boost the …

[PDF][PDF] Pilot study: MinION™-based identification of antibiotic resistance genes from 16S rRNA sequences

NH Bach, HTT Mai, NTK Linh - jmp.huemed-univ.edu.vn
Abstract Background: The MinIONTM is a portable DNA sequencing device that can
sequence 16S rRNA genes. 16S rRNA genes are found in all bacteria and can be used to …