As a histone acetyltransferase, lysine acetyltransferase 8 (KAT8) participates in diverse
biological processes. However, the effect of KAT8 on oocyte maturation in mice remains …

Research question Does double blastocyst vitrification and warming affect pregnancy rates
from embryos subjected to PGT-A testing? Design This is a retrospective observational …

Human oocyte maturation arrest represents one of the severe conditions for female patients
with primary infertility. However, the genetic factors underlying this human disease remain …

The distances between sister kinetochores at the metaphase II stage for aberrantly
segregating chromosomes were reduced from 1.3±0.7 µm in young mice to 0.8±0.3 µm in …

Fertility is declining worldwide and many couples are turning towards assisted reproductive
technologies (ART) to conceive babies. Organisms that propagate via sexual reproduction …

In dividing cells, accurate chromosome segregation depends on sister chromatid cohesion,
protein linkages that are established during DNA replication. Faithful chromosome …

Chromosome segregation during oocyte meiosis is highly error prone in mammals. Whereas
control mechanisms at work during meiosis I have been studied quite extensively, our …

During evolution, each lineage follows its own independent path of accumulating genome
variation. Variation exists at both sequence and structural level-the latter representing …

Chromosome segregation in female germ cells and early embryonic blastomeres is known
to be highly prone to errors. The resulting aneuploidy is therefore the most frequent reason …

Infertility is a major reproductive health issue that affects one in six couples worldwide.
Aneuploidy, the deviation from a balanced chromosome complement, is the leading genetic …