Abstract Bovine Lactoferrin (BLf) binds to Ca $\sp {2+} $-dependent high affinity binding
sites on isolated rat hepatocytes, and is vigorously endocytosed (McAbee et. al. 1994 …

Genetic engineering has been employed in the development of a purification system for
recombinant proteins, such as glutathione S-transferase (GST) and green fluorescent …

Construction of a full length bovine lactoferrin (bLf) cDNA (bLf nt6-2348) in a eukaryotic
expression vector allowed expression of bLf transcript and protein in transfected cells, and …

Metal complexes are at the heart of many biological processes. Remarkably few structural
motifs are used by Nature to accomplish such diverse functions as oxidation and reduction …

Helicobacter pylori (H. pylori) is a worldwide infection that affects millions of people. Some
people develop only minor symptoms or even no symptoms at all, whereas others complain …

Mastitis is most critical disease in dairy cows and causes huge cost in the dairy industry. To
prevent and treat it, it is important to understand the mechanisms of immune function in the …

BACKGROUND 0004 Cerebral edema, an increase in brain tissue water content, is
responsible for significant morbidity and mortality in many different disease states, including …

Lactoferrin is an iron transport protein. Upon binding iron, the two domains in the N terminal
half of the molecule move together. Previous work has shown that this domain closure …

We have recently demonstrated that the 1CF11 monoclonal antibody bound human milk
lactoferrin (hLf) through the recognition of two distinct portions of the molecule, namely the N …

Isolated rat hepatocytes bind and internalize bovine lactoferrin (Lf) and its bound iron in a C
2+-dependent manner by the major subunit, rat hepatic lectin-1 (RHL-1), of the …