Maternal immune activation and neuroinflammation in human neurodevelopmental disorders

VX Han, S Patel, HF Jones, RC Dale - Nature Reviews Neurology, 2021 - nature.com
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …

The gut microbiome and mental health: advances in research and emerging priorities

AP Shoubridge, JM Choo, AM Martin, DJ Keating… - Molecular …, 2022 - nature.com
The gut microbiome exerts a considerable influence on human neurophysiology and mental
health. Interactions between intestinal microbiology and host regulatory systems have now …

Immune dysregulation in autism spectrum disorder: what do we know about it?

MA Robinson-Agramonte, E Noris García… - International journal of …, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a group of complex multifactorial neurodevelopmental
disorders characterized by a wide and variable set of neuropsychiatric symptoms, including …

Impacts of consumption of ultra-processed foods on the maternal-child health: a systematic review

PG Oliveira, JM Sousa, DGF Assuncao… - Frontiers in …, 2022 - frontiersin.org
Background and Aims Changes in eating patterns have been leading to an increase in the
consumption of ultra-processed foods (UPF), negatively impacting the quality of the diet and …

A review on the vagus nerve and autonomic nervous system during fetal development: searching for critical windows

F Cerritelli, MG Frasch, MC Antonelli… - Frontiers in …, 2021 - frontiersin.org
The autonomic nervous system (ANS) is one of the main biological systems that regulates
the body's physiology. Autonomic nervous system regulatory capacity begins before birth as …

Considerations toward an epigenetic and common pathways theory of mental disorder.

JT Nigg - Journal of Psychopathology and Clinical Science, 2023 - psycnet.apa.org
Psychopathology emerges from the dynamic interplay of physiological and mental
processes and ecological context. It can be seen as a failure of recursive, homeostatic …

Malnutrition and the microbiome as modifiers of early neurodevelopment

EJL Coley, EY Hsiao - Trends in neurosciences, 2021 - cell.com
Malnutrition refers to a dearth, excess, or altered differential ratios of calories,
macronutrients, or micronutrients. Malnutrition, particularly during early life, is a pressing …

[HTML][HTML] Maternal high-fat diet modifies myelin organization, microglial interactions, and results in social memory and sensorimotor gating deficits in adolescent mouse …

M Bordeleau, LF de Cossío, C Lacabanne… - Brain, Behavior, & …, 2021 - Elsevier
Prenatal exposure to maternal high-fat diet (mHFD) acts as a risk factor for various
neurodevelopmental alterations in the progeny. Recent studies in mice revealed that mHFD …

Genetics and epigenetics of one-carbon metabolism pathway in autism spectrum disorder: a sex-specific brain epigenome?

V Tisato, JA Silva, G Longo, I Gallo, AV Singh, D Milani… - Genes, 2021 - mdpi.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition affecting
behavior and communication, presenting with extremely different clinical phenotypes and …

[HTML][HTML] Microglial functional alteration and increased diversity in the challenged brain: Insights into novel targets for intervention

MÈ Tremblay - Brain, behavior, & immunity-health, 2021 - Elsevier
Microglia are the resident immune cells of the central nervous system (CNS) parenchyma,
which perform beneficial physiological roles across life. These immune cells actively …