Towards network-guided neuromodulation for epilepsy

RJ Piper, RM Richardson, G Worrell, DW Carmichael… - Brain, 2022 - academic.oup.com
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …

Defining epileptogenic networks: contribution of SEEG and signal analysis

F Bartolomei, S Lagarde, F Wendling, A McGonigal… - …, 2017 - Wiley Online Library
Epileptogenic networks are defined by the brain regions involved in the production and
propagation of epileptic activities. In this review we describe the historical, methodologic …

Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology

RS Fisher, JH Cross, JA French, N Higurashi… - …, 2017 - Wiley Online Library
Summary The International League Against Epilepsy (ILAE) presents a revised operational
classification of seizure types. The purpose of such a revision is to recognize that some …

Regional and global connectivity disturbances in focal epilepsy, related neurocognitive sequelae, and potential mechanistic underpinnings

DJ Englot, PE Konrad, VL Morgan - Epilepsia, 2016 - Wiley Online Library
Epilepsy is among the most common brain network disorders, and it is associated with
substantial morbidity and increased mortality. Although focal epilepsy was traditionally …

An overview of deep learning techniques for epileptic seizures detection and prediction based on neuroimaging modalities: Methods, challenges, and future works

A Shoeibi, P Moridian, M Khodatars… - Computers in biology …, 2022 - Elsevier
Epilepsy is a disorder of the brain denoted by frequent seizures. The symptoms of seizure
include confusion, abnormal staring, and rapid, sudden, and uncontrollable hand …

Epileptogenic zone localization using magnetoencephalography predicts seizure freedom in epilepsy surgery

DJ Englot, SS Nagarajan, BS Imber, KP Raygor… - …, 2015 - Wiley Online Library
Objective The efficacy of epilepsy surgery depends critically upon successful localization of
the epileptogenic zone. Magnetoencephalography (MEG) enables noninvasive detection of …

Connectomics and graph theory analyses: novel insights into network abnormalities in epilepsy

E Gleichgerrcht, M Kocher, L Bonilha - Epilepsia, 2015 - Wiley Online Library
The assessment of neural networks in epilepsy has become increasingly relevant in the
context of translational research, given that localized forms of epilepsy are more likely to be …

A modular brain-on-a-chip for modelling epileptic seizures with functionally connected human neuronal networks

A Pelkonen, R Mzezewa, L Sukki, T Ryynänen… - Biosensors and …, 2020 - Elsevier
Epilepsies are a group of neurological disorders characterised by recurrent epileptic
seizures. Seizures, defined as abnormal transient discharges of neuronal activity, can affect …

Dynamical mechanisms of interictal resting-state functional connectivity in epilepsy

J Courtiol, M Guye, F Bartolomei… - Journal of …, 2020 - Soc Neuroscience
Drug-resistant focal epilepsy is a large-scale brain networks disorder characterized by
altered spatiotemporal patterns of functional connectivity (FC), even during interictal resting …

Network perspectives on epilepsy using EEG/MEG source connectivity

P Van Mierlo, Y Höller, NK Focke… - Frontiers in neurology, 2019 - frontiersin.org
The evolution of EEG/MEG source connectivity is both, a promising, and controversial
advance in the characterization of epileptic brain activity. In this narrative review we …