Lessons for COVID-19 immunity from other coronavirus infections
A Sariol, S Perlman - Immunity, 2020 - cell.com
A key goal to controlling coronavirus disease 2019 (COVID-19) is developing an effective
vaccine. Development of a vaccine requires knowledge of what constitutes a protective …
vaccine. Development of a vaccine requires knowledge of what constitutes a protective …
MERS coronavirus outbreak: Implications for emerging viral infections
A Al-Omari, AA Rabaan, S Salih, JA Al-Tawfiq… - … and infectious disease, 2019 - Elsevier
In September 2012, a novel coronavirus was isolated from a patient who died in Saudi
Arabia after presenting with acute respiratory distress and acute kidney injury. Analysis …
Arabia after presenting with acute respiratory distress and acute kidney injury. Analysis …
COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective
and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 …
and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 …
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes
Type 1 IFNs (IFN-I) generally protect mammalian hosts from virus infections, but in some
cases, IFN-I is pathogenic. Because IFN-I is protective, it is commonly used to treat virus …
cases, IFN-I is pathogenic. Because IFN-I is protective, it is commonly used to treat virus …
[HTML][HTML] Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses
Coronaviruses (CoVs) are a large family of enveloped, positive-strand RNA viruses. Four
human CoVs (HCoVs), the non-severe acute respiratory syndrome (SARS)-like HCoVs …
human CoVs (HCoVs), the non-severe acute respiratory syndrome (SARS)-like HCoVs …
[HTML][HTML] Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection
KA Kulcsar, CM Coleman, SE Beck, MB Frieman - JCI insight, 2019 - ncbi.nlm.nih.gov
Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 in Saudi
Arabia and has caused over 2400 cases and more than 800 deaths. Epidemiological …
Arabia and has caused over 2400 cases and more than 800 deaths. Epidemiological …
Clinical features of patients infected with the 2019 novel coronavirus (COVID-19) in Shanghai, China
M Cao, D Zhang, Y Wang, Y Lu, X Zhu, Y Li, H Xue… - MedRxiv, 2020 - medrxiv.org
ABSTRACT Background Since mid-December 2019, a cluster of pneumonia-like diseases
caused by a novel coronavirus, now designated COVID-19 by the WHO, emerged in Wuhan …
caused by a novel coronavirus, now designated COVID-19 by the WHO, emerged in Wuhan …
[HTML][HTML] IL-6 and CD8+ T cell counts combined are an early predictor of in-hospital mortality of patients with COVID-19
M Luo, J Liu, W Jiang, S Yue, H Liu, S Wei - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Fatal cases of COVID-19 are increasing globally. We retrospectively
investigated the potential of immunologic parameters as early predictors of COVID-19 …
investigated the potential of immunologic parameters as early predictors of COVID-19 …
Immune responses to Middle East respiratory syndrome coronavirus during the acute and convalescent phases of human infection
HS Shin, Y Kim, G Kim, JY Lee, I Jeong… - Clinical Infectious …, 2019 - academic.oup.com
Background An understanding of immune responses against the Middle East respiratory
syndrome (MERS) is important for the development of treatments and preventive measures …
syndrome (MERS) is important for the development of treatments and preventive measures …
Host immune response and immunobiology of human SARS-CoV-2 infection
S Kumar, R Nyodu, VK Maurya, SK Saxena - Coronavirus Disease 2019 …, 2020 - Springer
One of the most serious viral outbreaks of the decade, infecting humans, originated from the
city of Wuhan, China, by the end of December 2019, has left the world shaken up. It is the …
city of Wuhan, China, by the end of December 2019, has left the world shaken up. It is the …