Although several pharmacological options to treat depression are currently available,
approximately one third of patients who receive antidepressant medications do not respond …

Objective To explore the reasons behind the recent increase in antidepressant prescribing
in the United Kingdom. Design Detailed retrospective analysis of data on general …

Objective: We evaluated the effectiveness of Electroconvulsive Therapy (ECT) in the
treatment of Bipolar Disorder (BD) in a large sample of bipolar patients with drug resistant …

This review examines the role of trauma in psychiatric morbidity and analogous
psychoneurobiological changes. Trauma is a necessary criterion for Post-Traumatic Stress …

Background Psychiatric disorders are substantially associated with reduced quality of life
and increased mortality. Depression and anxiety are two of the most common psychiatric …

Depression is a potentially life-threatening disorder affecting millions of people across the
globe. It is a huge burden to both the individual and society, costing over£ 9 billion in 2000 …

Background Based on findings that major depressive disorder (MDD) is associated to
decreased dorsolateral prefrontal cortical (DLPFC) activity; interventions that increase …

These guidelines for the treatment of unipolar depressive disorders systematically review
available evidence pertaining to the biological treatment of patients with major depression …

Introduction Migraine prophylactic therapy has changed over recent years with the
development and approval of monoclonal antibodies (mAbs) targeting the calcitonin gene …

Abstract Major Depressive Disorder (MDD) is a psychiatric disorder characterized by high
comorbidity with cardiovascular disease. Furthermore, a combination of high heart rate (HR) …