The possible dose-dependency for the antidepressant effect of selective serotonin reuptake
inhibitors (SSRIs) remains controversial. We believe we have conducted the first …

Background: Guideline recommendations for the pharmacologic treatment of personality
disorder lack consensus, particularly for emotionally unstable personality disorder (EUPD) …

Selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment for major
depressive disorder (MDD), yet their mechanisms of action are not fully understood and their …

Many drugs used for chronic illnesses can contribute to dry eye syndrome, and elderly
patients who have dry eye may concurrently be on systemic medications that worsen the …

Background Antidepressant prescribing is increasing worldwide, prompting policy
interventions and targets to halt the rise. Aim To examine time trends in GP antidepressant …

Cognitive deficits are core symptoms of depression. This study aims to investigate whether
neurofeedback (NF) training can improve working memory (WM) performance in patients …

Background The UK Quality and Outcomes Framework (QOF) rewards practices for
measuring symptom severity in patients with depression, but the endorsed scales have not …

Psychological interventions for mood disorders can be divided into 'skilled'and 'simple '.
Psychoeducation belongs to the latter group: a simple and illness-focused therapy with …

Objective: This meta-analysis reviewed data on the efficacy and effective-ness of second-
generation antidepressants for preventing major depression relapse and recurrence during …

Non-steroidal anti-inflammatory drugs (NSAIDs) require further investigation given mixed
results regarding efficacy. We critically and systematically reviewed the literature to …