Characterization and therapeutic use of extracellular vesicles derived from platelets

T Spakova, J Janockova, J Rosocha - International Journal of Molecular …, 2021 - mdpi.com
Autologous blood products, such as platelet-rich plasma (PRP), are gaining increasing
interest in different fields of regenerative medicine. Although growth factors, the main …

[HTML][HTML] Interplay between hypoxia and extracellular vesicles in cancer and inflammation

M Venturella, M Criscuoli, F Carraro, A Naldini… - Biology, 2021 - mdpi.com
Hypoxia is a severe stress condition often observed in cancer and chronically inflamed cells
and tissues. Extracellular vesicles play pivotal roles in these pathological processes and …

EV‐ADD, a database for EV‐associated DNA in human liquid biopsy samples

T Tsering, M Li, Y Chen, A Nadeau… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) play a key role in cellular communication both in physiological
conditions and in pathologies such as cancer. Emerging evidence has shown that EVs are …

Simple and fast SEC-based protocol to isolate human plasma-derived extracellular vesicles for transcriptional research

LS Gaspar, MM Santana, C Henriques… - … Therapy Methods & …, 2020 - cell.com
Extracellular vesicles (EVs) are membranous structures that protect RNAs from damage
when circulating in complex biological fluids, such as plasma. RNAs are extremely specific …

miR-10b and miR-223-3p in serum microvesicles signal progression from prediabetes to type 2 diabetes

M Parrizas, X Mundet, C Castaño, S Canivell… - Journal of …, 2020 - Springer
Purpose Type 2 diabetes frequently remains undiagnosed for years, whereas early
detection of affected individuals would facilitate the implementation of timely and cost …

EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling

NC Buntsma, A Gąsecka, YB Roos, TG van Leeuwen… - Platelets, 2022 - Taylor & Francis
Citrate is the recommended anticoagulant for studies on plasma extracellular vesicles (EVs).
Because citrate incompletely blocks platelet activation and the release of platelet-derived …

2020 White paper on recent issues in bioanalysis: BMV of hybrid assays, acoustic MS, HRMS, data integrity, endogenous compounds, microsampling and microbiome …

H Neubert, SC Alley, A Lee, W Jian, M Buonarati… - Bioanalysis, 2021 - Taylor & Francis
The 14th edition of the Workshop on Recent Issues in Bioanalysis (14th WRIB) was held
virtually on June 15–29, 2020 with an attendance of over 1000 representatives from …

Extracellular vesicles from human plasma for biomarkers discovery: Impact of anticoagulants and isolation techniques

V Bettio, E Mazzucco, A Antona, S Cracas, M Varalda… - Plos one, 2023 - journals.plos.org
Extracellular vesicles (EVs) isolated from plasma are increasingly recognized as promising
circulating biomarkers for disease discovery and progression, as well as for therapeutic drug …

The exosome as a novel predictive/diagnostic biomarker of rejection in the field of transplantation

M Mirzakhani, M Mohammadnia-Afrouzi, M Shahbazi… - Clinical …, 2019 - Elsevier
Finding a non-invasive biomarker to monitor allograft status after transplantation could
contribute to better control of the post-transplant status of transplant recipients and, if …

Extracellular vesicles: New players in the mechanisms of sepsis-and COVID-19-related thromboinflammation

M Schiavello, B Vizio, O Bosco, E Pivetta… - International Journal of …, 2023 - mdpi.com
Sepsis and COVID-19 patients often manifest an imbalance in inflammation and
coagulation, a complex pathological mechanism also named thromboinflammation, which …