Regenerating myofiber directs Tregs and Th17 responses in inflamed muscle through the intrinsic TGF-β signaling-mediated IL-6 production

T Huang, JW Huang, ZH Liao, HQ Lan… - American Journal …, 2022 - journals.physiology.org
Transforming growth factor-b (TGF-b) is considered to be an important immune regulatory
cytokine. However, it remains unknown whether and how the muscle fiber specific-TGF-b …

Expression of immune markers of white sturgeon (Acipenser transmontanus) during Veronaea botryosa infection at different temperatures

E Soto, MD Fast, SL Purcell, DD Coleman… - … and Physiology Part D …, 2022 - Elsevier
Systemic phaeohyphomycosis caused by Veronaea botryosa is one of the most important
emergent diseases to affect sturgeon aquaculture in North America. White sturgeon …

Different effectiveness of fungal pathogen-associated molecular patterns (PAMPs) in activating rat peritoneal mast cells

P Żelechowska, E Brzezińska-Błaszczyk, J Agier… - Immunology …, 2022 - Elsevier
Mast cells (MCs) are the first immune cell type that can contact with the external
environment, where they may rapidly sense the presence of pathogens. These cells are …

Endogenous neutralization of TGF-β and IL-6 ameliorates septic arthritis by altering RANKL/OPG interaction in lymphocytes

R Ghosh, R Dey, R Sawoo, W Haque, B Bishayi - Molecular Immunology, 2022 - Elsevier
Septic arthritis is an inflammatory joint disease caused by S. aureus. Hematogenous entry of
the bacteria to the synovium produces pro-inflammatory cytokines TGF-β and IL-6, which …

Non-Coding RNAs in CD4+ T Cells: New Insights Into the Pathogenesis of Systemic Lupus Erythematosus

X Gao, L Liu, X Min, S Jia, M Zhao - Frontiers in Immunology, 2020 - frontiersin.org
Non-coding RNAs (ncRNAs) are indispensable for CD4+ T cell differentiation and functions.
By directly or indirectly regulating immune gene expression, ncRNAs give flexible …

Cytokine network analysis of immune responses before and after autologous dendritic cell and tumor cell vaccine immunotherapies in a randomized trial

GI Nistor, RO Dillman - Journal of Translational Medicine, 2020 - Springer
Background In a randomized phase II trial conducted in patients with metastatic melanoma,
patient-specific autologous dendritic cell vaccines (DCV) were associated with longer …

[HTML][HTML] The NKL-code for innate lymphoid cells reveals deregulated expression of NKL homeobox genes HHEX and HLX in anaplastic large cell lymphoma (ALCL)

S Nagel, C Pommerenke, RAF MacLeod, C Meyer… - Oncotarget, 2020 - ncbi.nlm.nih.gov
NKL homeobox genes encode developmental transcription factors and display an NKL-code
according to their physiological expression pattern in hematopoiesis. Here, we analyzed …

Analysis of the white sturgeon (Acipenser transmontanus) immune response during immunostimulation and Veronaea botryosa infection

E Soto, D Coleman, Z Yazdi, SL Purcell… - … and Physiology Part D …, 2021 - Elsevier
Systemic phaeohyphomycosis caused by Veronaea botryosa is regarded as an important
emerging mycotic disease of sturgeon aquaculture. However, no vaccines or treatments are …

Steroid receptor coactivators in Treg and Th17 cell biology and function

Y Gilad, O Shimon, SJ Han, DM Lonard… - Frontiers in …, 2024 - frontiersin.org
Steroid receptor coactivators (SRCs) are master regulators of transcription that play key
roles in human physiology and pathology. SRCs are particularly important for the regulation …

Dexamethasone alleviates pulmonary sarcoidosis by regulating the TGF-β/Smad3 signaling to promote Th17/Treg cell rebalance

Y Zhang, X Jiang, Q Wang, J Wu, J Zhou - Cellular Immunology, 2024 - Elsevier
Pulmonary sarcoidosis is an immune-mediated disorder closely related to Th17/Treg cell
imbalance. Dexamethasone has been shown to regulate inflammation and immune …