Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

The term 'old age'generally refers to a period characterized by profound changes in human
physiological functions and susceptibility to disease that accompanies the final years of a …

The identification and validation of drugs that promote health during aging (“geroprotectors”)
are key to the retardation or prevention of chronic age‐related diseases. Here, we found that …

Aging in humans is an incredibly complex biological process that leads to increased
susceptibility to various diseases. Understanding which genes are associated with healthy …

Illumina is the leading sequencing platform in the next-generation sequencing (NGS) market
globally. In recent years, MGI Tech has presented a series of new sequencers, including …

Maintenance of protein homeostasis degrades with age, contributing to aging-related
decline and disease. Previous studies have primarily surveyed transcriptional aging …

Context.—The National Institutes of Health Genotype-Tissue Expression (GTEx) project was
developed to elucidate how genetic variation influences gene expression in multiple normal …

Aging can be conceptualized as the stochastic accumulation of damage and loss of
resilience leading to organism demise. Resilience mechanisms that repair, recycle or …

COVID-19 is prevalent in the elderly. Old individuals are more likely to develop pneumonia
and respiratory failure due to alveolar damage, suggesting that lung senescence may …

Aging is a major risk factor for late-onset Alzheimer's disease (LOAD). How aging
contributes to the development of LOAD remains elusive. In this study, we examined multiple …