[HTML][HTML] The spike glycoprotein of SARS-CoV-2: A review of how mutations of spike glycoproteins have driven the emergence of variants with high transmissibility and …

PFN Souza, FP Mesquita, JL Amaral… - International journal of …, 2022 - Elsevier
Abstract Late in 2019, SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2)
emerged, causing an unknown type of pneumonia today called coronaviruses disease 2019 …

SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells

H Zhao, L Lu, Z Peng, LL Chen, X Meng… - Emerging microbes & …, 2022 - Taylor & Francis
ABSTRACT The novel SARS-CoV-2 Omicron variant (B. 1.1. 529), first found in early
November 2021, has sparked considerable global concern and it has> 50 mutations, many …

The P681H mutation in the spike glycoprotein of the alpha variant of SARS-CoV-2 escapes IFITM restriction and is necessary for type I interferon resistance

MJ Lista, H Winstone, HD Wilson, A Dyer… - Journal of …, 2022 - Am Soc Microbiol
The appearance of new dominant variants of concern (VOC) of severe acute respiratory
syndrome coronavirus type 2 (SARS-CoV-2) threatens the global response to the …

Cell and animal models for SARS-CoV-2 research

E Bestion, P Halfon, S Mezouar, JL Mège - Viruses, 2022 - mdpi.com
During the last two years following the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic, development of potent antiviral drugs and vaccines has been a …

Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant

KA Ryan, KR Bewley, RJ Watson, C Burton… - PLoS …, 2023 - journals.plos.org
The mutation profile of the SARS-CoV-2 Omicron (lineage BA. 1) variant posed a concern for
naturally acquired and vaccine-induced immunity. We investigated the ability of prior …

SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B. 1 strain in human cells with low ACE2 expression

D Niemeyer, S Stenzel, T Veith, S Schroeder… - PLoS …, 2022 - journals.plos.org
Epidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) variants of concern (VOCs) Alpha and Delta are more transmissible …

Pathogenicity of SARS-CoV-2 Omicron (R346K) variant in Syrian hamsters and its cross-neutralization with different variants of concern

S Mohandas, PD Yadav, G Sapkal, AM Shete… - …, 2022 - thelancet.com
Summary Background SARS-CoV-2 Omicron variant is rampantly spreading across the
globe. We assessed the pathogenicity and immune response generated by BA. 1.1 sub …

SARS‐CoV‐2 in animals: susceptibility of animal species, risk for animal and public health, monitoring, prevention and control

EFSA Panel on Animal Health and Welfare … - EFSA …, 2023 - Wiley Online Library
The epidemiological situation of SARS‐CoV‐2 in humans and animals is continually
evolving. To date, animal species known to transmit SARS‐CoV‐2 are American mink …

Infection-or AZD1222 vaccine-mediated immunity reduces SARS-CoV-2 transmission but increases Omicron competitiveness in hamsters

JR Port, CK Yinda, JC Riopelle, ZA Weishampel… - Nature …, 2023 - nature.com
Limited data is available on the effect of vaccination and previous virus exposure on the
nature of SARS-CoV-2 transmission and immune-pressure on variants. To understand the …

The SARS-CoV-2 Alpha variant exhibits comparable fitness to the D614G strain in a Syrian hamster model

M Cochin, L Luciani, F Touret, JS Driouich… - Communications …, 2022 - nature.com
Abstract Late 2020, SARS-CoV-2 Alpha variant emerged in United Kingdom and gradually
replaced G614 strains initially involved in the global spread of the pandemic. In this study …