Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19

S Reis, MI Metzendorf, R Kuehn… - Cochrane Database …, 2023 - cochranelibrary.com
Background Oral nirmatrelvir/ritonavir (Paxlovid) aims to avoid severe COVID‐19 in
asymptomatic people or those with mild symptoms, thereby decreasing hospitalization and …

Efficacy and safety of molnupiravir treatment for COVID-19: a systematic review and meta-analysis of randomized controlled trials

F Tian, Q Feng, Z Chen - International Journal of Antimicrobial Agents, 2023 - Elsevier
Introduction At present, there are some differences in the research results of molnupiravir.
The purpose of this study was to evaluate the efficacy and safety of molnupiravir in the …

[HTML][HTML] Seeing the T cell immunity of SARS-CoV-2 and SARS-CoV: believing the epitope-oriented vaccines

C Yue, P Wang, J Tian, GF Gao, K Liu… - International Journal of …, 2023 - ncbi.nlm.nih.gov
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the
end of 2019 stimulated vigorous research efforts in immunology and vaccinology. In addition …

Is antiviral treatment at the acute phase of COVID-19 effective for decreasing the risk of long-COVID? A systematic review

C Fernández-de-Las-Peñas, J Torres-Macho… - Infection, 2024 - Springer
Purpose Preliminary evidence suggests a potential effect of antiviral medication used during
the acute COVID-19 phase for preventing long-COVID. This review investigates if having …

[HTML][HTML] Long COVID or Post-COVID-19 Condition: Past, Present and Future Research Directions

C Fernández-de-Las-Peñas, AV Raveendran… - Microorganisms, 2023 - mdpi.com
The presence of symptoms after an acute SARS-CoV-2 infection (long-COVID) has become
a worldwide healthcare emergency but remains underestimated and undertreated due to a …

Paxlovid reduces the risk of Long COVID in patients six months after hospital discharge

Y Wang, D Zhao, W Xiao, J Shi… - Journal of medical …, 2023 - pubmed.ncbi.nlm.nih.gov
Paxlovid reduces the risk of Long COVID in patients six months after hospital discharge
Paxlovid reduces the risk of Long COVID in patients six months after hospital discharge J Med …

[PDF][PDF] Efficacy and safety of azvudine in patients with COVID-19: a systematic review and meta-analysis

Z Chen, F Tian - Heliyon, 2023 - cell.com
Introduction Azivudine has undergone a few randomized controlled trials (RCTs) as of late.
This study aimed to assess the COVID-19 treatment with azvudine's efficacy and safety …

Evaluation of oral small molecule drugs for the treatment of COVID-19 patients: a systematic review and network meta-analysis

Z Chen, F Tian - Annals of Medicine, 2023 - Taylor & Francis
Introduction At present, there are some randomized controlled trials (RCTs) of oral small
molecule drugs. The purpose of this study was to evaluate the efficacy and safety of oral …

Nirmatrelvir/ritonavir for COVID-19: an overview of systematic reviews

M Cruciani, I Pati, F Masiello, S Pupella… - Journal of …, 2024 - academic.oup.com
Objectives A reappraisal of the validity of the conclusions of systematic reviews (SRs)
related to nirmatrelvir/ritonavir for the treatment of COVID-19. Methods An overview of SRs …

[HTML][HTML] Effectiveness of Nirmatrelvir-Ritonavir for the Prevention of COVID-19–Related Hospitalization and Mortality: A Systematic Literature Review

AS Cha-Silva, MB Gavaghan, T Bergroth… - American Journal of …, 2024 - journals.lww.com
Background: Nirmatrelvir/ritonavir (NMV/r) is an oral antiviral drug used to treat mild-to-
moderate coronavirus disease 2019 (COVID-19) in patients aged 12 years or older at high …