The complex biological mechanisms underlying human brain aging remain incompletely
understood. This study investigated the genetic architecture of three brain age gaps (BAG) …

Background Observational studies suggest an association between sarcopenia-related traits
and brain aging, but whether this association reflects a causal relationship remains unclear …

Adolescents exhibit remarkable heterogeneity in the structural architecture of brain
development. However, due to limited large-scale longitudinal neuroimaging studies …

Primate brain evolution has involved prominent expansions of the cerebral cortex, with
largest effects observed in the human lineage. Such expansions were accompanied by fine …

The lifespan growth of the functional connectome remains unknown. Here, we assemble
task-free functional and structural magnetic resonance imaging data from 33,250 individuals …

Background Anthocyanin and blueberry intakes positively associated with cognitive function
in population-based studies and cognitive benefits in randomized controlled trials of adults …

Decades of research has revealed a relationship between childhood socioeconomic status
(SES) and brain development at the structural and functional levels. Of particular note is the …

Myelinated axons form long-range connections that enable rapid communication between
distant brain regions, but how genetics governs the strength and organization of these …

Introduction Aging influences the morphology of the central nervous system. While several
previous studies focused on morphometric changes of the supratentorial parts …

The connection between the gut microbiota and brain structure changes is still unclear. We
conducted a Mendelian randomization (MR) study to examine the bidirectional causality …