Influence of environmental exposure on human epigenetic regulation
CJ Marsit - Journal of Experimental Biology, 2015 - journals.biologists.com
Environmental toxicants can alter epigenetic regulatory features such as DNA methylation
and microRNA expression. As the sensitivity of epigenomic regulatory features may be …
and microRNA expression. As the sensitivity of epigenomic regulatory features may be …
[HTML][HTML] Carcinogenicity assessment: Addressing the challenges of cancer and chemicals in the environment
Cancer is a key public health concern, being the second leading cause of worldwide
morbidity and mortality after cardiovascular diseases. At the global level, cancer prevalence …
morbidity and mortality after cardiovascular diseases. At the global level, cancer prevalence …
Pubertal timing and breast cancer risk in the Sister Study cohort
Background Earlier age at menarche is an established risk factor for breast cancer. While
age at menarche has been fairly stable over the past half-century, age at breast …
age at menarche has been fairly stable over the past half-century, age at breast …
The role of adolescent lifestyle habits in biological aging: A prospective twin study
Background: Adolescence is a stage of fast growth and development. Exposures during
puberty can have long-term effects on health in later life. This study aims to investigate the …
puberty can have long-term effects on health in later life. This study aims to investigate the …
Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls
Epigenetic age is an indicator of biological aging, capturing the impact of environmental and
behavioral influences across time on cellular function. Deviance between epigenetic age …
behavioral influences across time on cellular function. Deviance between epigenetic age …
How the genome got a life span
M Lappé, H Landecker - New genetics and society, 2015 - Taylor & Francis
In the space of little more than a decade, ideas of the human genome have shifted
significantly, with the emergence of the notion that the genome of an individual changes with …
significantly, with the emergence of the notion that the genome of an individual changes with …
Bisphenol A: a concise review of literature and a discussion of health and regulatory implications
Background/Aim: Bisphenol A (BPA) is a ubiquitous substance found in a wide array of
consumer products and healthcare consumables, and at low doses in drinking water …
consumer products and healthcare consumables, and at low doses in drinking water …
Early life affects late-life health through determining DNA methylation across the lifespan: A twin study
Background Previous findings for the genetic and environmental contributions to DNA
methylation variation were for limited age ranges only. We investigated the lifespan …
methylation variation were for limited age ranges only. We investigated the lifespan …
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty
DL Cousminer, E Stergiakouli, DJ Berry… - Human molecular …, 2014 - academic.oup.com
Little is known about genes regulating male puberty. Further, while many identified pubertal
timing variants associate with age at menarche, a late manifestation of puberty, and body …
timing variants associate with age at menarche, a late manifestation of puberty, and body …
Early life exposures and adult cancer risk
MA Clarke, CE Joshu - Epidemiologic reviews, 2017 - academic.oup.com
Very little is known about the influence of early life exposures on adult cancer risk. The
purpose of this narrative review was to summarize the epidemiologic evidence relating early …
purpose of this narrative review was to summarize the epidemiologic evidence relating early …