Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Recent studies have
identified the key role of crosstalk between dysregulated epithelial cells, mesenchymal …

Transforming growth factor-β (TGF-β) signaling is an important pathway for promoting the
pathogenesis of inflammatory diseases, including cancer. The roles of TGF-β signaling are …

Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease with
pathophysiological characteristics of transforming growth factor-β (TGF-β), and reactive …

Idiopathic pulmonary fibrosis (IPF) is an irreversible and life-threatening lung disease of
unknown etiology presenting only a few treatment options. TGF-β signaling orchestrates a …

Although alveolar epithelial cells play a critical role in the pathogenesis of pulmonary
fibrosis, few practical in vitro models exist to study them. Here, we established a novel in …

Biomarkers are detectable molecules that can reflect specific physiological states of cells,
organs, and organisms and therefore be regarded as indicators for specific diseases. And …

As epigenetic modifications, lactylation and N6-methyladenosine (m6A) have attracted wide
attention. Arsenite is an environmental pollutant that has been proven to induce idiopathic …

Idiopathic pulmonary fibrosis (IPF) is a fatal disease with high mortality and limited effective
therapy. Herein, we reported that fluvoxamine, a selective serotonin reuptake inhibitor …

Background: Immune checkpoint inhibitors (ICIs), such as programmed cell death protein 1
(PD-1)/programmed death-ligand 1 (PD-L1), have been widely applied in clinical and …

Pulmonary fibrosis, a sequela of lung injury resulting from severe infection such as severe
acute respiratory syndrome‐like coronavirus (SARS‐CoV‐2) infection, is a kind of life …