Human height is a representative phenotype to elucidate genetic architecture. However, the
majority of large studies have been performed in European population. To investigate the …

Fine-mapping to plausible causal variation may be more effective in multi-ancestry cohorts,
particularly in the MHC, which has population-specific structure. To enable such studies, we …

The first step towards realizing personalized healthcare is to catalog the genetic variations in
a population. Since the dissemination of individual-level genomic information is strictly …

Abstract We initiate the Westlake BioBank for Chinese (WBBC) pilot project with 4,535 whole-
genome sequencing (WGS) individuals and 5,841 high-density genotyping individuals, and …

Despite substantial advances in disease genetics, studies to date have largely focused on
individuals of European descent. This limits further discoveries of novel functional genetic …

Skin pigmentation is a classic example of a polygenic trait that has experienced directional
selection in humans. Genome-wide association studies have identified well over a hundred …

Dietary habits are important factors in our lifestyle, and confer both susceptibility to and
protection from a variety of human diseases. We performed genome-wide association …

The diversity in our genome is crucial to understanding the demographic history of
worldwide populations. However, we have yet to know whether subtle genetic differences …

Integrating genomic data of multiple cancers allows de novo cancer grouping and
elucidating the shared genetic basis across cancers. Here, we conduct the pan-cancer and …

We present the initial phase of the Korean Genome Project (Korea1K), including 1094 whole
genomes (sequenced at an average depth of 31×), along with data of 79 quantitative clinical …