Background Most adults with major depressive disorder (MDD) fail to achieve remission with
index pharmacological treatment. Moreover, at least half will not achieve and sustain …

Major depressive disorder is one of the most common psychiatric illnesses in the United
States, with an estimated lifetime prevalence of up to 17%. 1 Affected individuals are at high …

Treatment‐resistant depression (TRD) is common and associated with multiple serious
public health implications. A consensus definition of TRD with demonstrated predictive utility …

Objectives. This 2013 update of the practice guidelines for the biological treatment of
unipolar depressive disorders was developed by an international Task Force of the World …

This practical book has given tens of thousands of clinicians and students a comprehensive
introduction to mindfulness and its clinical applications. The book describes the …

BackgroundElectroconvulsive therapy (ECT) is considered to be the most effective treatment
in severe major depression. The identification of reliable predictors of ECT response could …

Context Selective serotonin reuptake inhibitors (SSRIs) are often described as having a
delayed onset of effect in the treatment of depression. However, some trials have reported …

These practical guidelines for the biological treatment of unipolar depressive disorders in
primary care settings were developed by an international Task Force of the World …

Background A growing number of observational and epidemiological studies have
suggested that mental illness, in particular mood disorders, is associated with reduced …

Background Prediction of therapeutic outcome of repetitive transcranial magnetic stimulation
(rTMS) treatment is an important purpose that eliminates financial and psychological …