Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

The craniofacial region contains skin, bones, cartilage, the temporomandibular joint (TMJ),
teeth, periodontal tissues, mucosa, salivary glands, muscles, nerves, and blood vessels …

Salivary gland dysfunction worsens the quality of life, but treatment for restoration of salivary
gland function is limited. Although previous reports have demonstrated the therapeutic …

Simple Summary The extensive array of applications in 3D culture models closely mimics
the precise physiological conditions of in vivo settings, enabling the investigation of …

The oral cavity is inhabited by abundant microbes which continuously interact with the host
and influence the host's health. Such host-microbe interactions (HMI) are dynamic and …

Regenerative medicine holds promise to cure radiation-induced salivary hypofunction, a
chronic side effect in patients with head and neck cancers, therefore reliable preclinical …

Radiotherapy has served as a double-edged sword in medicine. While it has extended the
life of many cancer survivors, its iatrogenic offside effects on healthy tissues often leave a …

Salivary gland hypofunction (SGH) caused by systemic disease, drugs, aging, and
radiotherapy for head and neck cancer can cause dry mouth, which increases the risk of …

Dental pulp stem cells (DPSCs) have emerged as a promising tool with great potential for
use in tissue regeneration and engineering. Some of the main advantages of these cells are …

Objectives This study aimed to evaluate the level of oxidative stress (OS) in human and rat
chronic sialadenitis (CS) of the submandibular gland (SMG). Method We collected human …