Positive controls in adults and children support that very few, if any, new neurons are born in the adult human hippocampus
Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies
identified the adult neural stem cells and found important links between adult neurogenesis …
identified the adult neural stem cells and found important links between adult neurogenesis …
Current state of the art for enhancing urine biomarker discovery
M Harpole, J Davis, V Espina - Expert review of Proteomics, 2016 - Taylor & Francis
Introduction: Urine is a highly desirable biospecimen for biomarker analysis because it can
be collected recurrently by non-invasive techniques, in relatively large volumes. Urine …
be collected recurrently by non-invasive techniques, in relatively large volumes. Urine …
Neurovascular injury with complement activation and inflammation in COVID-19
The underlying mechanisms by which severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) leads to acute and long-term neurological manifestations remains obscure …
(SARS-CoV-2) leads to acute and long-term neurological manifestations remains obscure …
Germinal centre-driven maturation of B cell response to mRNA vaccination
Germinal centres (GC) are lymphoid structures in which B cells acquire affinity-enhancing
somatic hypermutations (SHM), with surviving clones differentiating into memory B cells …
somatic hypermutations (SHM), with surviving clones differentiating into memory B cells …
A human cell atlas of fetal chromatin accessibility
INTRODUCTION In recent years, the single-cell genomics field has made incredible
progress toward disentangling the cellular heterogeneity of human tissues. However, the …
progress toward disentangling the cellular heterogeneity of human tissues. However, the …
Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer
Circulating tumour DNA (ctDNA) in blood plasma is an emerging tool for clinical cancer
genotyping and longitudinal disease monitoring. However, owing to past emphasis on …
genotyping and longitudinal disease monitoring. However, owing to past emphasis on …
ImmuCellAI: a unique method for comprehensive T‐cell subsets abundance prediction and its application in cancer immunotherapy
The distribution and abundance of immune cells, particularly T‐cell subsets, play pivotal
roles in cancer immunology and therapy. T cells have many subsets with specific function …
roles in cancer immunology and therapy. T cells have many subsets with specific function …
APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer
JL McCann, A Cristini, EK Law, SY Lee, M Tellier… - Nature Genetics, 2023 - nature.com
The single-stranded DNA cytosine-to-uracil deaminase APOBEC3B is an antiviral protein
implicated in cancer. However, its substrates in cells are not fully delineated. Here …
implicated in cancer. However, its substrates in cells are not fully delineated. Here …
Single-cell transcriptomic profiling of the aging mouse brain
The mammalian brain is complex, with multiple cell types performing a variety of diverse
functions, but exactly how each cell type is affected in aging remains largely unknown. Here …
functions, but exactly how each cell type is affected in aging remains largely unknown. Here …
Gene expression across mammalian organ development
M Cardoso-Moreira, J Halbert, D Valloton, B Velten… - Nature, 2019 - nature.com
The evolution of gene expression in mammalian organ development remains largely
uncharacterized. Here we report the transcriptomes of seven organs (cerebrum, cerebellum …
uncharacterized. Here we report the transcriptomes of seven organs (cerebrum, cerebellum …