Cationic Lipid Pairs Enhance Liver-to-Lung Tropism of Lipid Nanoparticles for In Vivo mRNA Delivery

G Zeng, Z He, H Yang, Z Gao, X Ge, L Liu… - … Applied Materials & …, 2024 - ACS Publications
Much of current clinical interest has focused on mRNA therapeutics for the treatment of lung-
associated diseases, such as infections, genetic disorders, and cancers. However, the safe …

Dynamic Covalent Hydrogel as a Single‐dose Vaccine Adjuvant for Sustained Antigen Release and Significantly Elevated Humoral Immunity

Z Shi, Z Gao, X Zhuang, X Si, Z Huang… - Advanced …, 2024 - Wiley Online Library
Vaccine is the most important way for fighting against infection diseases. However, multiple
injections and unsatisfied immune responses are the main obstacles for current vaccine …

Organ‐Targeted Ionizable Lipid Nanoparticles Facilitate Sequence‐Activated Fluorogenic Probe for Precise Imaging of Inflammatory Liver Disease

Y Bian, Y Zhang, B Hu, Y Huang, W Liang, Q Yuan… - Small, 2024 - Wiley Online Library
Activatable near‐infrared (NIR) fluorogenic probes offer a potent tool for real‐time, in situ
detection of hepatic biomarkers, significantly advancing the precision in diagnosing …