Parkinson's disease (PD) is a global health challenge, yet historically studies of PD have
taken place predominantly in European populations. Recent genetics research conducted in …

The discovery of a pathogenic variant in the alpha-synuclein (SNCA) gene in the Contursi
kindred in 1997 indisputably confirmed a genetic cause in a subset of Parkinson's disease …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons in the substantia nigra. The pathological hallmark of PD is the …

Objective Parkinson's disease (PD) is a neurodegenerative disorder with complex etiology.
Multiple genetic and environmental factors have been associated with PD, but most PD risk …

Background: As a chronic degenerative disorder of the central nervous system that affects
both motor and non-motor systems, Parkinson's disease (PD) is very complex, and …

Phthalates are a group of neurotoxicants with cognitive-disrupting potentials. Given the
structural diversity of phthalates, the corresponding neurotoxicity is dramatically altered. To …

Soot nanoparticles (SNPs) are black carbon prevalent in atmospheric environment with
significant impacts on public health, leading to neurodegenerative diseases including …

Abstract Background Patients with Parkinson's disease (PD) have consistently demonstrated
brain structure abnormalities, indicating the presence of shared etiological and pathological …

Abstract Background Most Parkinson's disease (PD) loci have shown low prevalence in the
Indian population, highlighting the need for further research. Objective The aim of this study …

Epigenetic dysregulation that leads to alterations in gene expression and is suggested to be
one of the key pathophysiological factors of Parkinson's disease (PD). Here, we found that α …