Deciphering the role of monocyte and monocyte distribution width (MDW) in COVID-19: an updated systematic review and meta-analysis

D Ligi, B Lo Sasso, BM Henry, M Ciaccio… - Clinical Chemistry and …, 2023 - degruyter.com
The SARS-CoV-2 infection is characterized by both systemic and organ hyper-
thromboinflammation, with a clinical course ranging from mild up-to critical systemic …

What is the impact of circulating histones in COVID-19: a systematic review

D Ligi, RV Giglio, BM Henry, G Lippi… - Clinical Chemistry and …, 2022 - degruyter.com
The infectious respiratory condition COVID-19 manifests a clinical course ranging from
mild/moderate up-to critical systemic dysfunction and death linked to thromboinflammation …

Circulating histones contribute to monocyte and MDW alterations as common mediators in classical and COVID-19 sepsis

D Ligi, B Lo Sasso, RV Giglio, R Maniscalco… - Critical Care, 2022 - Springer
Objective Histone proteins are physiologically involved in DNA packaging and gene
regulation but are extracellularly released by neutrophil/monocyte extracellular traps and …

Monocyte distribution width alterations and cytokine storm are modulated by circulating histones

D Ligi, B Lo Sasso, C Della Franca… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives Extracellular histone levels are associated with the severity of many human
pathologies, including sepsis and COVID-19. This study aimed to investigate the role of …

Impaired fibrinolysis in severe Covid-19 infection is detectable in early stages of the disease

O Watson, S Pillai, M Howard… - Clinical …, 2022 - content.iospress.com
BACKGROUND: A significant degree of mortality and morbidity in Covid-19 is due to
thromboembolic disease. Coagulopathy has been well described in critically unwell patients …

Fibrin structure, viscoelasticity and lysis face the interplay of biorelevant polyions

E Komorowicz, K Kolev - Current Opinion in Hematology, 2022 - journals.lww.com
Fibrin structure, viscoelasticity and lysis face the interpl... : Current Opinion in Hematology
Fibrin structure, viscoelasticity and lysis face the interplay of biorelevant polyions : Current …

COVID-19 and Biomarkers: The Contribution of the Journal

M Plebani - Journal of Clinical Medicine, 2023 - mdpi.com
Three years after coronavirus disease 2019 (COVID-19) was declared a pandemic by the
World Health Organization (WHO), several features of the pathogenesis and innate immune …

[HTML][HTML] Роль нейтрофильных экстрацеллюлярных сетей (NETs) в иммунопатогенезе тяжелого COVID-19: потенциальные иммунотерапевтические стратегии …

ИВ Нестерова, МГ Атажахова, ЮВ Тетерин… - Инфекция и …, 2023 - cyberleninka.ru
Роль нейтрофильных гранулоцитов (НГ) в патогенезе COVID-19 связана с
рекрутированием НГ в очаги воспаления, активацией их функций и усиленным …

[HTML][HTML] The role of neutrophil extracellular traps (NETs) in the immunopathogenesis of severe COVID-19: potential immunotherapeutic strategies regulating NET …

IV Nesterova, MG Atazhakhova, YV Teterin… - Russian Journal of …, 2023 - iimmun.ru
The role of neutrophil granulocytes (NG) in the pathogenesis of COVID-19 is associated with
the NG recruitment into inflammatory foci, activation of their functions and enhanced …

[PDF][PDF] Circulating Histones Induce Inflammatory Responses in Monocytes: Effects of Heparins as Histone-Neutralizing Agents

F Mannello - core.ac.uk
Histones are key components for chromatin physiological functions but extracellularly
mobilized during pathological processes [1]. Acting as endogenous damage-associated …