Cognitive and motivational selectivity in healthy aging

LT Swirsky, J Spaniol - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Normal aging is associated with a reduction in the selectivity of cognitive processes such as
attention and memory. This loss of selectivity is attributed to diminished inhibition and …

[HTML][HTML] Isometric exercise facilitates attention to salient events in women via the noradrenergic system

M Mather, R Huang, D Clewett, SE Nielsen, R Velasco… - NeuroImage, 2020 - Elsevier
The locus coeruleus (LC) regulates attention via the release of norepinephrine (NE), with
levels of tonic LC activity constraining the intensity of phasic LC responses. In the current …

Noradrenergic responsiveness supports selective attention across the adult lifespan

MJ Dahl, M Mather, MC Sander… - Journal of …, 2020 - Soc Neuroscience
Selectively attending to relevant information while blocking out distractors is crucial for goal-
directed behavior, yet with advancing age, deficits emerge in attentional selectivity …

Aging impairs reactive attentional control but not proactive distractor inhibition.

AJ Kim, J Senior, S Chu, M Mather - Journal of experimental …, 2024 - psycnet.apa.org
Older adults tend to be more prone to distraction compared with young adults, and this age-
related deficit has been attributed to a deficiency in inhibitory processing. However, recent …

Interference and attentional switching in aging.

CA Schumann, NJ Evans, GA Robinson - Neuropsychology, 2023 - psycnet.apa.org
Objective: Diffusion decision modeling (DDM) is a validated cognitive modeling method that
has been used to provide insights into why older adults are slower than younger adults on a …

The decline in intrinsic connectivity between the salience network and locus coeruleus in older adults: Implications for distractibility

TH Lee, SH Kim, B Katz, M Mather - Frontiers in Aging Neuroscience, 2020 - frontiersin.org
We examined functional connectivity between the locus coeruleus (LC) and the salience
network in healthy young and older adults to investigate why people become more prone to …

Age differences in vulnerability to distraction under arousal.

SN Gallant, KA Durbin, M Mather - Psychology and aging, 2020 - psycnet.apa.org
Aging affects brain circuitry involved in both inhibition and arousal. In this study, we tested
whether older adults are more or less prone to distraction from emotionally arousing events …

Behavioral and fMRI evidence that arousal enhances bottom-up selectivity in young but not older adults

SN Gallant, BL Kennedy, SL Bachman, R Huang… - Neurobiology of …, 2022 - Elsevier
The locus coeruleus-noradrenergic system integrates signals about arousal states
throughout the brain and helps coordinate cognitive selectivity. However, age-related …

The Locus Coeruleus: Where Cognitive and Emotional Processing Meet the Eye

R Huang, D Clewett - Modern Pupillometry: Cognition, Neuroscience, and …, 2024 - Springer
The pupil offers a window into how arousal shapes the way we think, learn, and behave. Yet,
arousal is a complex and multifaceted construct, leaving many open questions about the …

Locus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical alzheimer's disease

J Pahl, PC Prokopiou, E Bueichekú, AP Schultz… - Alzheimer's Research & …, 2024 - Springer
Autopsy work reported that neuronal density in the locus coeruleus (LC) provides neural
reserve against cognitive decline in dementia. Recent neuroimaging and pharmacological …