Acetylation of histones and transcription-related factors
DE Sterner, SL Berger - Microbiology and molecular biology …, 2000 - Am Soc Microbiol
The state of chromatin (the packaging of DNA in eukaryotes) has long been recognized to
have major effects on levels of gene expression, and numerous chromatin-altering …
have major effects on levels of gene expression, and numerous chromatin-altering …
Targeting epigenetics in cancer
RL Bennett, JD Licht - Annual review of pharmacology and …, 2018 - annualreviews.org
Alterations of genes regulating epigenetic processes are frequently found as cancer drivers
and may cause widespread alterations of DNA methylation, histone modification patterns, or …
and may cause widespread alterations of DNA methylation, histone modification patterns, or …
Dissecting the regulatory circuitry of a eukaryotic genome
FCP Holstege, EG Jennings, JJ Wyrick, TI Lee… - Cell, 1998 - cell.com
Genome-wide expression analysis was used to identify genes whose expression depends
on the functions of key components of the transcription initiation machinery in yeast …
on the functions of key components of the transcription initiation machinery in yeast …
Curcumin as a MicroRNA regulator in cancer: a review
AA Momtazi, F Shahabipour, S Khatibi… - Reviews of Physiology …, 2016 - Springer
Curcumin is a natural dietary polyphenol for which anti-tumor effects have been
documented. Anti-inflammatory and antioxidant properties of curcumin, along with its …
documented. Anti-inflammatory and antioxidant properties of curcumin, along with its …
Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.
The transcriptional adaptor protein Gcn5 has been identified as a nuclear histone
acetyltransferase (HAT). Although recombinant yeast Gcn5 efficiently acetylates free …
acetyltransferase (HAT). Although recombinant yeast Gcn5 efficiently acetylates free …
ATP-dependent chromatin-remodeling complexes
The importance of histones and chromatin structure in the regulation of eukaryotic gene
transcription has become much more widely accepted over the past few years. It has been …
transcription has become much more widely accepted over the past few years. It has been …
[HTML][HTML] NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM‐related cofactor Tra1p
S Allard, RT Utley, J Savard, A Clarke, P Grant… - The EMBO …, 1999 - embopress.org
Post‐translational acetylation of histone H4 N‐terminal tail in chromatin has been
associated with several nuclear processes including transcription. We report the purification …
associated with several nuclear processes including transcription. We report the purification …
Role of microRNAs in the therapeutic effects of curcumin in non-cancer diseases
Curcumin is a bioactive polyphenol occurring in the rhizomes of Curcuma longa. It is well-
reputed for its chemopreventive and anticancer properties; however, recent evidence has …
reputed for its chemopreventive and anticancer properties; however, recent evidence has …
Characterization of the imitation switch subfamily of ATP-dependent chromatin-remodeling factors in Saccharomyces cerevisiae
T Tsukiyama, J Palmer, CC Landel… - Genes & …, 1999 - genesdev.cshlp.org
We have identified and characterized two Imitation Switch genes in Saccharomyces
cerevisiae, ISW1 and ISW2, which are highly related to Drosophila ISWI, encoding the …
cerevisiae, ISW1 and ISW2, which are highly related to Drosophila ISWI, encoding the …
[HTML][HTML] Structural basis of transcription reduction by a promoter-proximal+ 1 nucleosome
J Abril-Garrido, C Dienemann, F Grabbe, T Velychko… - Molecular Cell, 2023 - cell.com
At active human genes, the+ 1 nucleosome is located downstream of the RNA polymerase II
(RNA Pol II) pre-initiation complex (PIC). However, at inactive genes, the+ 1 nucleosome is …
(RNA Pol II) pre-initiation complex (PIC). However, at inactive genes, the+ 1 nucleosome is …