Magnetic resonance imaging–guided vs computed tomography–guided stereotactic body radiotherapy for prostate cancer: the MIRAGE randomized clinical trial

AU Kishan, TM Ma, JM Lamb, M Casado… - JAMA …, 2023 - jamanetwork.com
Importance Magnetic resonance imaging (MRI) guidance offers multiple theoretical
advantages in the context of stereotactic body radiotherapy (SBRT) for prostate cancer …

History of technological advancements towards MR-Linac: the future of image-guided radiotherapy

N Rammohan, JW Randall, P Yadav - Journal of Clinical Medicine, 2022 - mdpi.com
Image-guided radiotherapy (IGRT) enables optimal tumor targeting and sparing of organs-at-
risk, which ultimately results in improved outcomes for patients. Magnetic resonance …

Radiation injury and gut microbiota-based treatment

W Wang, B Cui, Y Nie, L Sun, F Zhang - Protein & Cell, 2024 - academic.oup.com
The exposure to either medical sources or accidental radiation can cause varying degrees
of radiation injury (RI). RI is a common disease involving multiple human body parts and• …

Radiotherapy-triggered proteolysis targeting chimera prodrug activation in tumors

C Yang, Y Yang, Y Li, Q Ni, J Li - Journal of the American …, 2022 - ACS Publications
Proteolysis targeting chimera (PROTAC) is an emerging protein degradation strategy, which
shows excellent advantages in targeting those so-called “undruggable” proteins. However …

Patterns of failure following external beam radiotherapy with or without an additional focal boost in the randomized controlled FLAME trial for localized prostate cancer

VH Groen, K Haustermans, FJ Pos, C Draulans… - European Urology, 2022 - Elsevier
Background Focal dose escalation in external beam radiotherapy (EBRT) showed an
increase in 5-yr biochemical disease-free survival in the Focal Lesion Ablative Microboost in …

Clinical implementation of magnetic resonance imaging simulation for radiation oncology planning: 5 year experience

D Moore-Palhares, L Ho, L Lu, B Chugh, D Vesprini… - radiation …, 2023 - Springer
Purpose Integrating magnetic resonance (MR) into radiotherapy planning has several
advantages. This report details the clinical implementation of an MR simulation (MR …

Clinical application of MR-Linac in tumor radiotherapy: a systematic review

X Liu, Z Li, Y Yin - Radiation Oncology, 2023 - Springer
Recent years have seen both a fresh knowledge of cancer and impressive advancements in
its treatment. However, the clinical treatment paradigm of cancer is still difficult to implement …

[HTML][HTML] Investigation and benchmarking of U-Nets on prostate segmentation tasks

S Bhandary, D Kuhn, Z Babaiee, T Fechter… - … Medical Imaging and …, 2023 - Elsevier
In healthcare, a growing number of physicians and support staff are striving to facilitate
personalized radiotherapy regimens for patients with prostate cancer. This is because …

miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response

P Biswal, A Lalruatfela, SK Behera, S Biswal… - IUBMB …, 2024 - Wiley Online Library
MicroRNAs (miRNAs) are a class of noncoding RNAs of about 19–25 nucleotides, which
serve as critical modulators of various cellular and biological processes by target gene …

Towards accurate and precise image-guided radiotherapy: clinical applications of the MR-Linac

JW Randall, N Rammohan, IJ Das, P Yadav - Journal of Clinical …, 2022 - mdpi.com
Advances in image-guided radiotherapy have brought about improved oncologic outcomes
and reduced toxicity. The next generation of image guidance in the form of magnetic …