Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Efficiently balancing excess reactive oxygen species (ROS) caused by various factors on the
ocular surface is a promising strategy for preventing the development of ocular surface …

With the global prevalence of diabetes mellitus over recent decades, more patients suffered
from various diabetic complications, including diabetic ocular surface diseases that may …

The increased prevalence of type 2 diabetes mellitus (T2DM) and life expectancy of diabetic
patients fosters the worldwide prevalence of retinopathy and nephropathy, two major …

Diabetic keratopathy (DK) is a common, but underdiagnosed, ocular complication of
diabetes mellitus (DM) that has a significant economic burden. It is characterised by …

There is a number of systemic diseases affecting the cornea. These include endocrine
disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections …

The cornea is the most densely innervated and sensitive tissue in the body. The cornea is
exclusively innervated by C-and A-delta fibers, including mechano-nociceptors that are …

Diabetes mellitus (DM) has been emerging as one of the most serious health problems
worldwide. Ocular complications of DM are currently one of the major causes of blindness in …

Ocular complications from diabetes mellitus are common. Diabetic keratopathy, the most
frequent clinical condition affecting the human cornea, is a potentially sight-threatening …