The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of long COVID
J Li, Y Zhou, J Ma, Q Zhang, J Shao, S Liang… - … and Targeted Therapy, 2023 - nature.com
There have been hundreds of millions of cases of coronavirus disease 2019 (COVID-19),
which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With …
which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With …
Neuropsychiatric disorders following SARS-CoV-2 infection
PJ Harrison, M Taquet - Brain, 2023 - academic.oup.com
Several large-scale electronic health records studies have reported increased diagnostic
rates for neuropsychiatric disorders following Coronavirus disease 2019 [COVID-19 or …
rates for neuropsychiatric disorders following Coronavirus disease 2019 [COVID-19 or …
[HTML][HTML] Serotonin reduction in post-acute sequelae of viral infection
AC Wong, AS Devason, IC Umana, TO Cox… - Cell, 2023 - cell.com
Post-acute sequelae of COVID-19 (PASC," Long COVID") pose a significant global health
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
Persistent complement dysregulation with signs of thromboinflammation in active Long Covid
Long Covid is a debilitating condition of unknown etiology. We performed multimodal
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …
[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …
and subjective components. They are common and debilitating, and can affect the ability to …
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2
Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We
describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed …
describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed …
A study of gene expression in the living human brain
LE Liharska, YJ Park, K Ziafat, L Wilkins, H Silk… - medRxiv, 2023 - medrxiv.org
A goal of medical research is to determine the molecular basis of human brain health and
illness. One way to achieve this goal is through observational studies of gene expression in …
illness. One way to achieve this goal is through observational studies of gene expression in …
Challenges and opportunities in long COVID research
RE Hamlin, CA Blish - Immunity, 2024 - cell.com
Long COVID (LC) is a condition in which patients do not fully recover from the initial SARS-
CoV-2 infection but rather have persistent or new symptoms for months to years following …
CoV-2 infection but rather have persistent or new symptoms for months to years following …
Genetic risk factors for severe and fatigue dominant long COVID and commonalities with ME/CFS identified by combinatorial analysis
Background Long COVID is a debilitating chronic condition that has affected over 100
million people globally. It is characterized by a diverse array of symptoms, including fatigue …
million people globally. It is characterized by a diverse array of symptoms, including fatigue …