D-dimer is a soluble fibrin degradation product deriving from the plasmin-mediated
degradation of cross-linked fibrin. D-dimer can hence be considered a biomarker of …

Background: How diagnostic strategies for suspected pulmonary embolism (PE) perform in
relevant patient subgroups defined by sex, age, cancer, and previous venous …

Background Validated diagnostic algorithms in patients with suspected pulmonary embolism
are often not used correctly or only benefit subgroups of patients, leading to overuse of …

Background: Clinical probability assessment is combined with d-dimer testing to exclude
pulmonary embolism (PE). Purpose: To compare the test characteristics of gestalt (a …

ABSTRACT D-dimers are formed by the breakdown of fibrinogen and fibrin during
fibrinolysis. D-dimer analysis is critical for the diagnosis of deep vein thrombosis, pulmonary …

Acute deep vein thrombosis (DVT) and pulmonary embolism (PE) represent two expressions
of a similar clinical pathological process, often referred to as venous throm-boembolism …

OBJECTIVE. Pulmonary CT angiography (CTA) is the imaging modality of choice in
suspected acute pulmonary embolism (PE). Current pulmonary CTA techniques involve ever …

D-dimer is a global indicator of coagulation activation and fibrinolysis and, therefore, an
indirect marker of thrombotic activity. The utility of D-dimer measurement has been …

Background Few studies evaluated the performance of noninvasive diagnostic strategies for
suspected acute pulmonary embolism (PE) in pregnant women. Objectives The aim of this …

Deep venous thrombosis and pulmonary embolism represent two expressions of a similar
clinical pathological process traditionally referred to as venous thromboembolism. Several …