Osteoporosis, is the most common bone disorder worldwide characterized by low bone
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …

An expanding body of research asserts that the gut microbiota has a role in bone
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …

The data output from microbiome research is growing at an accelerating rate, yet mining the
data quickly and efficiently remains difficult. There is still a lack of an effective data structure …

Context Several small studies have suggested that the gut microbiome might influence
osteoporosis, but there is little evidence from human metabolomics studies to explain this …

Metabolites in the tumor microenvironment are a critical factor for tumor progression.
However, the lack of knowledge about the metabolic profile in the bone marrow (BM) …

The gastrointestinal tract is colonized by trillions of microorganisms, consisting of bacteria,
fungi, and viruses, known as the “second gene pool” of the human body. In recent years, the …

Bone is a mineralized and elastic connective tissue that provides fundamental functions in
the human body, including mechanical support to the muscles and joints, protection of vital …

Results: A total of 10,468 records were screened with 13 studies included in this review. In
healthy women, higher estrogen levels were found to be associated with a higher …

Although the gut microbiota has been reported to influence osteoporosis risk, the individual
species involved, and underlying mechanisms, remain largely unknown. We performed …

Postmenopausal osteoporosis (PMO) results from a reduction in bone mass and
microarchitectural deterioration in bone tissue due to estrogen deficiency, which may …