Lentiviral vectors (LVs) are potent tools for the delivery of genes of interest into mammalian
cells and are now commonly utilised within the growing field of cell and gene therapy for the …

The use of vaccination against the influenza virus remains the most effective method of
mitigating the significant morbidity and mortality caused by this virus. Antibodies elicited by …

Some filoviruses can be transmitted to humans by zoonotic spillover events from their
natural host and filovirus outbreaks have occured with increasing frequency in the last years …

Emerging viral diseases pose a threat to the global population as intervention strategies are
mainly limited to basic containment due to the lack of efficacious and approved vaccines and …

This protocol details a rapid and reliable method for the production and titration of high-titre
viral pseudotype particles with the SARS-CoV-2 spike protein (and D614G or other variants …

Background Highly pathogenic emerging and re-emerging viruses continuously threaten
lives worldwide. In order to provide prophylactic prevention from the emerging and re …

Background Pseudotyped virus systems that incorporate viral proteins have been widely
employed for the rapid determination of the effectiveness and neutralizing activity of drug …

Sporadic outbreaks of Ebola virus infection have been documented since the mid-Seventies
and viral exposure can lead to lethal haemorrhagic fever with case fatalities as high as 90 …

Serological assays detecting neutralising antibodies are important for determining the
immune responses following infection or vaccination and are also often considered a …

We developed an influenza hemagglutinin (HA) pseudotype library encompassing Influenza
A subtypes HA1-18 and Influenza B subtypes (both lineages) to be employed in influenza …