Application and comparison of lyophilisation protocols to enhance stable long-term storage of filovirus pseudotypes for use in antibody neutralisation tests

MM Neto, E Wright, N Temperton… - Journal of Applied …, 2023 - academic.oup.com
Aims Filoviruses encompass highly pathogenic viruses placing significant public health
burden on countries affected. Efforts for improved diagnostics and surveillance are needed …

A safe and reliable neutralization assay based on pseudovirus to measure neutralizing antibody titer against poliovirus

S Liu, D Song, H Bai, W Lu, X Dai, C Hao… - Journal of Medical …, 2017 - Wiley Online Library
With the promotion of inactivated poliomyelitis vaccine (IPV) and live attenuated oral
poliomyelitis vaccine (OPV), the global reported cases of poliomyelitis have reduced sharply …

[HTML][HTML] Evaluation of the effect of maternally derived antibody on response to MMR vaccine in Thai infants

S Hu, N Logan, J Puenpa, N Wanlapakorn… - Vaccine, 2022 - Elsevier
Background Although the number of measles cases declined globally in response to anti-
measles immunisation campaigns, measles has re-emerged. A review of current vaccination …

Cross-neutralisation of novel Bombali virus by Ebola virus antibodies and convalescent plasma using an optimised Pseudotype-based neutralisation assay

EM Bentley, S Richardson, M Derveni, P Rijal… - Tropical Medicine and …, 2021 - mdpi.com
Ebolaviruses continue to pose a significant outbreak threat, and while Ebola virus (EBOV)-
specific vaccines and antivirals have been licensed, efforts to develop candidates offering …

The application of pseudotypes to influenza pandemic preparedness

F Ferrara, E Molesti, N Temperton - Future Virology, 2015 - Taylor & Francis
Human and animal populations are constantly exposed to multiple influenza strains due to
zoonotic spillover and rapid viral evolution driven by intrinsic error-prone replication and …

Reservoir host studies of Lloviu virus: first isolation, sequencing and serology in Schreiber's bats in Europe

G Kemenesi, GE Tóth, M Mayora-Neto, S Scott… - Biorxiv, 2021 - biorxiv.org
Introductory Filoviruses are prime examples of emerging human pathogens that are
transmitted to humans by zoonotic spillover events. Since their initial discovery, filovirus …

Lentiviral vector stability and process purification based on modifications to the viral envelope

C Perry - 2021 - discovery.ucl.ac.uk
Lentiviral vectors (LV) are potent tools in delivering genetic information for vac-cines and
therapeutic benefits. Bioprocessing of LV remains challenging, with vec-tor generation …

Introducing EbolaCheck: potential for point-of-need infectious disease diagnosis

SA Moschos - Expert Review of Molecular Diagnostics, 2015 - Taylor & Francis
The 2013–2015 Ebolavirus disease humanitarian crisis has spurred the development of
laboratory-free, point-of-care nucleic acid testing solutions. EbolaCheck is an international …

Lyophilized lentiviral vector particles, compositions and methods

C Bauche, GO MBELE - 2015 - Google Patents
Methods of making lyophilized lentiviral vector particles are provided. Compositions
comprising lyophilized lentiviral vector particles are also provided. Methods of administering …

Ebolavirus: pseudotypes, libraries and standards

NJ Temperton, M Page - Future Virology, 2015 - Taylor & Francis
Globalization, accompanied by increasing levels of international travel and trade, climate
change, altered human behavior and demographics, is leading to the emergence of …